Evidence map›Paper›PMID 40733583›Full record

ArticleViruses2025

Epidemiological Profiles of Human Rabies Cases in Tunisia Between 2000 and 2022.

Amal Ayachi, Rym Benabdallah, Aida Bouratbine, Karim Aoun, Jihen Bensalem, Nourhen Basdouri, Samia Benmaiz, Farah Bassalah, Chaima Nouioui, Mohamed Soltani and 4 more

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Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Amal AyachiFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis 1007, Tunisia.
Rym BenabdallahLaboratory of Medical Parasitology, Biotechnology and Biomolecules, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Aida BouratbineLaboratory of Medical Parasitology, Biotechnology and Biomolecules, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.ORCID 0000-0001-7049-7030
Karim AounLaboratory of Medical Parasitology, Biotechnology and Biomolecules, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Jihen BensalemLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Nourhen BasdouriIndependent Researcher, Tunis 1000, Tunisia.
Samia BenmaizLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Farah BassalahLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Chaima NouiouiLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Mohamed SoltaniLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Khaled GhouiliLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Zied BouslemaLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.ORCID 0000-0002-9424-0704
Habib KharmechiIndependent Researcher, Tunis 1000, Tunisia.
Mariem HandousLaboratory of Epidemiology and Veterinary Microbiology, Group of Virology, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.ORCID 0000-0002-7494-0463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Tunisia, rabies is endemic and represents a significant public health issue. The objectives of our study were to describe the epidemiological and clinical profiles of human rabies cases and report the risk factors associated with their occurrence. We conducted a retrospective, descriptive, and analytical study of human rabies cases confirmed at the Rabies Laboratory of the Pasteur Institute in Tunis from January 2000 to November 2022. Temporal-spatial, sociodemographic, and clinical variables and factors related to the exposure context, post-exposure, and response were collected for each patient. A total of 58 human rabies cases were identified. The governorates of Kairouan and Nabeul were the most affected, with a predominance of rural areas (77%, 34/44). The highest number of cases was recorded between May and November (74%, 43/58). The cases predominantly involved males, with the most affected age group being individuals aged from 31 to 59 years (30%, 17/57). Rabies transmission was primarily due to dogs (86%, 43/50) and a single bite (55%, 32/58). After an average incubation period of 60.3 days, hydrophobia and behavioral disturbances were the most common symptoms. This study demonstrates that the risk of human rabies remains present in Tunisia, highlighting the need to improve awareness and post-exposure prophylaxis practices.

Indexed as

RabiesAdolescentAdultAgedAnimalsBites and StingsChildChild, PreschoolDogsFemaleHumansInfantMaleMiddle AgedRabies virusRetrospective Studiesclinical virologyrabieszoonosis

Identifiers

PMID40733583
PMCPMC12299497

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.