Evidence map›Paper›PMID 40733497›Full record

ArticleViruses2025

Retrointegration2023-Papers from the 7th International Conference on Retroviral Integration.

Alan N Engelman, Duane P Grandgenett, Goedele N Maertens, Kristine E Yoder, Mamuka Kvaratskhelia

Abstract readEditorial
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alan N EngelmanDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.ORCID 0000-0002-9709-2591
Duane P GrandgenettDepartment of Molecular Microbiology and Immunology, School of Medicine, Saint Louis University, St. Louis, MO 61304, USA.ORCID 0000-0003-1082-7629
Goedele N MaertensDepartment of Infectious Disease, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0002-1963-8026
Kristine E YoderDepartment of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Mamuka KvaratskheliaDivision of Infectious Disease, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.

Funding

Nuclear Localization of HIV-1 Preintegration ComplexesR01AI052014 · NIAID · DANA-FARBER CANCER INSTITUTE · PI ENGELMAN, ALAN N. · 2003 to 2025
$11.4M
Biochemical Mechanism of HIV DNA IntegrationR37AI039394 · NIAID · DANA-FARBER CANCER INST · PI Alan N. Engelman · 2010 to 2026
$10.2M
Ultra-potent HIV capsid inhibitorsR01AI157802 · NIAID · UNIVERSITY OF COLORADO DENVER · PI JAMES R FUCHS, Mamuka Kvaratskhelia · 2020 to 2026
$7.1M
Roles of HIV-1 capsid-binding FG-motif containing cellular cofactors in infectionR01AI162665 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Mamuka Kvaratskhelia, Gregory B Melikian · 2022 to 2026
$3.9M
Role of HIV-1 integrase in virion morphogenesis and its targeting by allosteric integrase inhibitorsR01AI184419 · NIAID · UNIVERSITY OF COLORADO DENVER · PI JAMES R FUCHS, Sebla B. Kutluay · 2024 to 2026
$2.4M
Visualization of HIV-1 integration in real timeR01AI150496 · NIAID · OHIO STATE UNIVERSITY · PI KRISTINE E YODER · 2020 to 2026
$2.3M
The Mechanics of Retroviral IntegrationR01AI126742 · NIAID · OHIO STATE UNIVERSITY · PI FISHEL, RICHARD, YODER, KRISTINE E · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI052014NIAID NIH HHS R01 AI126742NIAID NIH HHS R01 AI150496NIAID NIH HHS R01 AI157802NIAID NIH HHS R01 AI162665NIAID NIH HHS R01 AI184419NIAID NIH HHS R37 AI039394
6 · The paper itself

Abstract

The integration of retroviral DNA into host chromosomal DNA is a landmark event that demarcates the transition from the early steps of virus replication to post-integration gene expression and the assembly of new virus particles [...].

Indexed as

RetroviridaeVirus IntegrationAnimalsHumansVirus Replication

Identifiers

PMID40733497
PMCPMC12299400

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.