ArticleViruses2025
First Molecular Characterization of Sheep Pox Viruses in Northern Ghana, 2023.
Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Sheep pox (SP) is a contagious viral disease affecting sheep, characterized by fever, respiratory distress, hypogalactia, and skin lesions. In response to a series of outbreaks of pox-like lesions with morbidity (75%) and mortality (37%) rates among sheep in the Upper East Region of Ghana, nasal samples were obtained from affected sheep for diagnosis and characterization. The DNA extracted from these samples was tested using quantitative PCR (qPCR). Positive samples were subjected to further analysis for poxvirus marker genes using conventional PCR. Positive amplicons were sequenced, and phylogenetic analysis was conducted. The characterization and comparison of RPO30, GPCR, EEV glycoprotein, and B22R genes with other isolates demonstrated a close genetic relationship with sheep poxviruses (SPVs) identified in other African and Asian countries. This study represents the first comprehensive characterization of SPV in Ghana, and the data generated will be of significant interest to national and regional veterinary authorities.
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