Evidence map›Paper›PMID 40733094›Full record

ReviewPharmaceutics2025

Advances in Liposomal Drug Delivery: Multidirectional Perspectives on Overcoming Biological Barriers.

Żaneta Sobol, Rafał Chiczewski, Dorota Wątróbska-Świetlikowska

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Vaccine Adjuvants and Delivery Systems: A Comprehensive Review.International journal of molecular sciences · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Bridging bioactive metabolites ofFrontiers in pharmacology · 2026
    Review
  14. Article
  15. Review
  16. Nanovesicle-formulatedJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Żaneta SobolDepartment of Pharmaceutical Technology, Pomeranian Medical University in Szczecin, Rybacka 1, 70-204 Szczecin, Poland.
Rafał ChiczewskiDepartment of Pharmaceutical Technology, Pomeranian Medical University in Szczecin, Rybacka 1, 70-204 Szczecin, Poland.ORCID 0009-0002-7267-973X
Dorota Wątróbska-ŚwietlikowskaDepartment of Pharmaceutical Technology, Pomeranian Medical University in Szczecin, Rybacka 1, 70-204 Szczecin, Poland.ORCID 0000-0002-4570-025X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposomes represent a cornerstone of modern drug delivery systems due to their unique structural and physicochemical characteristics. Extensive research has refined their formulation, stability, and targeting capabilities, leading to numerous clinical applications, particularly in oncology. A key clinical feature is their ability to accumulate in malignant tissues via the enhanced permeability and retention effect, offering improved pharmacokinetics and reduced systemic toxicity. Advances in liposomal engineering, including PEGylation and ligand-based targeting, have significantly enhanced pharmacokinetic profiles and tissue specificity, minimizing off-target toxicity. The modern approach to nanocarrier-based drugs offers multidirectional perspectives on targeted therapy. Liposomes can bypass drug resistance mechanisms and provide controlled or stimuli-responsive drug release. Current trends in liposome research focus on hybrid nanocarriers, personalized medicine applications, and combination therapies.

Indexed as

liposomes modificationnanocarrier-based drug delivery systemstargeted therapy

Identifiers

PMID40733094
PMCPMC12298344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.