Evidence map›Paper›PMID 40733047›Full record

ArticlePharmaceutics2025

Development and Characterization of a New Oral Antileishmanial Bis(pyridine-2-Carboxamidine) Drug Through Innovative Dissolution Testing in Biorelevant Media Combined with Pharmacokinetic Studies.

Almudena Laguna, Borja Martínez-Alonso, Víctor Guarnizo-Herrero, J Jonathan Nué-Martinez, Christophe Dardonville, Santiago Torrado-Santiago, Carlos Torrado-Salmerón

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Almudena LagunaDepartment of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0009-0000-1857-5222
Borja Martínez-AlonsoDepartment of Biomedical Science, Faculty of Pharmacy, University of Alcalá de Henares, Ctra Madrid-Barcelona Km 33,600, 28805 Madrid, Spain.ORCID 0009-0002-9124-5507
Víctor Guarnizo-HerreroDepartment of Biomedical Science, Faculty of Pharmacy, University of Alcalá de Henares, Ctra Madrid-Barcelona Km 33,600, 28805 Madrid, Spain.ORCID 0000-0001-9323-3388
J Jonathan Nué-MartinezInstitute of Medicinal Chemistry, IQM-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0001-6483-6892
Christophe DardonvilleInstitute of Medicinal Chemistry, IQM-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0001-5395-1932
Santiago Torrado-SantiagoDepartment of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0000-0002-3273-2615
Carlos Torrado-SalmerónDepartment of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0000-0002-4123-3367

Funding

Agencia Estatal de Investigación (MCIN/AEI/10.13039/501100011033) PDC2022-133269-I00Agencia Estatal de Investigación (MCIN/AEI/10.13039/501100011033) PID2022-136438OB-I00
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antileishmanial drugbiorelevant mediacharacterizationpharmacokinetic studysurfactant

Identifiers

PMID40733047
PMCPMC12300650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.