Evidence map›Paper›PMID 40733033›Full record

ArticlePharmaceutics2025

Novel Lung Cell-Penetrating Peptide Targets Alveolar Epithelial Type II Cells, Basal Cells, and Ionocytes.

Jin Wen, Gajalakshmi Singuru, Jeffrey Stiltner, Sanjay Mishra, Kyle S Feldman, Kayla McCandless, Raymond Yurko, Kazi Islam, Ray Frizzell, Hisato Yagi and 2 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jin WenDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-8883-8443
Gajalakshmi SinguruDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Jeffrey StiltnerDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Sanjay MishraDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.ORCID 0000-0003-4449-0729
Kyle S FeldmanClinical Virology Laboratory, Yale New Haven Hospital, New Haven, CT 06510, USA.
Kayla McCandlessDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Raymond YurkoPeptide and Peptoid Synthesis Facility, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Kazi IslamPeptide and Peptoid Synthesis Facility, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Ray FrizzellDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Hisato YagiDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.ORCID 0000-0003-1460-4043
Jonathan M BrownConsultant, MPEG LA, L.L.C., Denver, CO 80206, USA.
Maliha ZahidDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-2986-9557

Funding

Targeting Underlying Pathophysiological Mechanisms to Develop Novel Therapies for Chronic Obstructive Lung DiseaseR01HL153407 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZAHID, MALIHA · 2020 to 2024
$3.0M
NHLBI NIH HHS HL153407NHLBI NIH HHS R01 HL153407
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alveolar type II cellsbasal cellscell-penetrating peptidesionocytessiRNA

Identifiers

PMID40733033
PMCPMC12298391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.