ArticlePolymers2025
Novel Core-Shell Aerogel Formulation for Drug Delivery Based on Alginate and Konjac Glucomannan: Rational Design Using Artificial Intelligence Tools.
Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Insights on the Generation of Polymeric Drug Carriers via Supercritical Fluid-Assisted Technologies.Materials (Basel, Switzerland) · 2026Review
- Emerging Gel Technologies for Atherosclerosis Research and Intervention.Gels (Basel, Switzerland) · 2026Review
- Mannans as Multifunctional Biopolymers: Structure, Properties, and Applications in Health and Industry.Polymers · 2025Review
- Hybrid Alginate-Based Polysaccharide Aerogels Microparticles for Drug Delivery: Preparation, Characterization, and Performance Evaluation.Gels (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This study explores novel alginate-konjac glucomannan core-shell aerogel particles for drug delivery systems fabricated via air-assisted coaxial prilling. A systematic approach is needed for the optimization of this method due to the numerous processing variables involved. This study investigated the influence of six variables: alginate and konjac glucomannan concentrations, compressed airflow, liquid pump pressures, and nozzle configuration. A hybrid software using Artificial Neural Networks and genetic algorithms was used to model and optimize the hydrogel formation, achieving a 100% desirable solution. The optimal formulation identified resulted in particles displaying a log-normal size distribution (
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Registered trials
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