Evidence map›Paper›PMID 40732668›Full record

ArticlePathogens (Basel, Switzerland)2025

The EGFR Signaling Pathway Is Involved in the Biliary Intraepithelial Neoplasia Associated with Liver Fluke Infection.

Dmitry Ponomarev, Oxana Zaparina, Anna Kovner, Elena Hadieva, Mikhail Persidskij, Maria Pakharukova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Liver FlukeBiomolecules · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dmitry PonomarevInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (ICG SB RAS), 10 Akad. Lavrentiev Ave., Novosibirsk 630090, Russia.ORCID 0000-0002-2951-5716
Oxana ZaparinaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (ICG SB RAS), 10 Akad. Lavrentiev Ave., Novosibirsk 630090, Russia.
Anna KovnerInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (ICG SB RAS), 10 Akad. Lavrentiev Ave., Novosibirsk 630090, Russia.ORCID 0000-0001-9543-9005
Elena HadievaClinical Hospital of the Khanty-Mansiysk Autonomus Okrug-Ugra, Khanty-Mansiysk 628013, Russia.
Mikhail PersidskijClinical Hospital of the Khanty-Mansiysk Autonomus Okrug-Ugra, Khanty-Mansiysk 628013, Russia.
Maria PakharukovaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (ICG SB RAS), 10 Akad. Lavrentiev Ave., Novosibirsk 630090, Russia.ORCID 0000-0003-1054-2068

Funding

Russian Science Foundation 24-25-00080
6 · The paper itself

Abstract

Foodborne trematode infections are recognized as a significant risk factor for cholangiocarcinoma (CCA) in endemic regions. Infection with the liver fluke

Indexed as

Bile Duct NeoplasmsCarcinoma in SituCholangiocarcinomaErbB ReceptorsOpisthorchiasisSignal TransductionAnimalsCell MovementCell ProliferationCricetinaeDisease Models, AnimalFemaleHumansMaleOpisthorchisToll-Like Receptor 4EGFR protein, humanErbB ReceptorsToll-Like Receptor 4carcinogenesisepidermal growth factor receptor (EGFR)excretory–secretory productH69 cholangiocytesmigrationOpisthorchis felineusproliferationToll-like receptor 4 (TLR4)

Identifiers

PMID40732668
PMCPMC12298937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.