Evidence map›Paper›PMID 40732539›Full record

ReviewSensors (Basel, Switzerland)2025

Functional Nanomaterials for Advanced Bioelectrode Interfaces: Recent Advances in Disease Detection and Metabolic Monitoring.

Junlong Ma, Siyi Yang, Zhihao Yang, Ziliang He, Zhanhong Du

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junlong MaThe Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Siyi YangThe Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Zhihao YangThe Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Ziliang HeThe Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Zhanhong DuThe Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.ORCID 0000-0001-6535-1424

Funding

Ministry of Science and Technology of China 2022ZD0209800
6 · The paper itself

Abstract

As critical interfaces bridging biological systems and electronic devices, the performance of bioelectrodes directly determines the sensitivity, selectivity, and reliability of biosensors. Recent advancements in functional nanomaterials (e.g., carbon nanomaterials, metallic nanoparticles, 2D materials) have substantially enhanced the application potential of bioelectrodes in disease detection, metabolic monitoring, and early diagnosis through strategic material selection, structural engineering, interface modification, and antifouling treatment. This review systematically examines the latest progress in nanomaterial-enabled interface design of bioelectrodes, with particular emphasis on performance enhancements in electrophysiological/electrochemical signal acquisition and multimodal sensing technologies. We comprehensively analyze cutting-edge developments in dynamic metabolic parameter monitoring for chronic disease management, as well as emerging research on flexible, high-sensitivity electrode interfaces for early disease diagnosis. Furthermore, this work focused on persistent technical challenges regarding nanomaterial biocompatibility and long-term operational stability while providing forward-looking perspectives on their translational applications in wearable medical devices and personalized health management systems. The proposed framework offers actionable guidance for researchers in this interdisciplinary field.

Indexed as

Biosensing TechniquesNanostructuresElectrochemical TechniquesElectrodesHumansMonitoring, PhysiologicWearable Electronic Devicesbioelectrodesdiagnosticselectrochemistryelectrophysiologymonitoringmultimodalitynanomaterialswearables

Identifiers

PMID40732539
PMCPMC12298287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.