Evidence map›Paper›PMID 40732534›Full record

ArticleSensors (Basel, Switzerland)2025

Transformer-Based Decomposition of Electrodermal Activity for Real-World Mental Health Applications.

Charalampos Tsirmpas, Stasinos Konstantopoulos, Dimitris Andrikopoulos, Konstantina Kyriakouli, Panagiotis Fatouros

Abstract readComparative Study
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Charalampos TsirmpasFeel Therapeutics Inc., San Francisco, CA 94108, USA.ORCID 0009-0000-9110-7716
Stasinos KonstantopoulosFeel Therapeutics Inc., San Francisco, CA 94108, USA.ORCID 0000-0002-2586-1726
Dimitris AndrikopoulosFeel Therapeutics Inc., San Francisco, CA 94108, USA.ORCID 0000-0001-7141-7661
Konstantina KyriakouliInstitute for Machine Learning, Johannes Kepler University, 4040 Linz, Austria.ORCID 0000-0002-6081-4423
Panagiotis FatourosFeel Therapeutics Inc., San Francisco, CA 94108, USA.ORCID 0000-0003-1685-0600

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decomposing Electrodermal Activity (EDA) into phasic (short-term, stimulus-linked responses) and tonic (longer-term baseline) components is essential for extracting meaningful emotional and physiological biomarkers. This study presents a comparative analysis of knowledge-driven, statistical, and deep learning-based methods for EDA signal decomposition, with a focus on in-the-wild data collected from wearable devices. In particular, the authors introduce the Feel Transformer, a novel Transformer-based model adapted from the Autoformer architecture, designed to separate phasic and tonic components without explicit supervision. The model leverages pooling and trend-removal mechanisms to enforce physiologically meaningful decompositions. Comparative experiments against methods such as Ledalab, cvxEDA, and conventional detrending show that the Feel Transformer achieves a balance between feature fidelity (SCR frequency, amplitude, and tonic slope) and robustness to noisy, real-world data. The model demonstrates potential for real-time biosignal analysis and future applications in stress prediction, digital mental health interventions, and physiological forecasting.

Indexed as

Deep LearningGalvanic Skin ResponseSignal Processing, Computer-AssistedWearable Electronic DevicesDecision Support Systems, ClinicalHumansMental Healthbiosignal processingdeep learningdigital mental healthelectrodermal activityphasic and tonic decompositionreal-world signal analysistime series detrendingtransformer modelswearable sensors

Identifiers

PMID40732534
PMCPMC12298303

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.