Evidence map›Paper›PMID 40732341›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Supercomputing Multi-Ligand Modeling, Simulation, Wavelet Analysis and Surface Plasmon Resonance to Develop Novel Combination Drugs: A Case Study of Arbidol and Baicalein Against Main Protease of SARS-CoV-2.

Hong Li, Hailong Su, Akari Komori, Shuxuan Yang, Hailang Luo, Angela Wei Hong Yang, Xiaomin Sun, Hongwei Li, Andrew Hung, Xiaoshan Zhao

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hong LiDepartment of Traditional Chinese Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.ORCID 0000-0002-3874-4860
Hailong SuSchool of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0002-5091-4033
Akari KomoriSchool of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia.ORCID 0000-0002-4097-6804
Shuxuan YangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0003-3237-1984
Hailang LuoSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Angela Wei Hong YangSchool of Health and Biomedical Sciences, STEM College, RMIT University, Bundoora, VIC 3083, Australia.ORCID 0000-0001-9345-4607
Xiaomin SunSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Hongwei LiSchool of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China.
Andrew HungSchool of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia.ORCID 0000-0003-3569-2951
Xiaoshan ZhaoDepartment of Traditional Chinese Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.

Funding

China Postdoctoral Science Foundation 2022M711534Guangdong Basic and Applied Basic Research Foundation 2021A1515110082Guangzhou Science and Technology Plan Project 2024B03J1343Joint Funds of National Natural Science Foundation of China U22A20365National Natural Science Foundation of China 82204812
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19structure-based multi-ligand molecular modelingsynergismToujie Quwen Granulesumifenovir

Identifiers

PMID40732341
PMCPMC12300969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.