Evidence map›Paper›PMID 40732327›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Selumetinib in Adult Neurofibromatosis 1 with Plexiform Neurofibroma.

Carlen A Yuen, Eleanor Chu, Ryan O'Connell, Bryan K Sun, Raj Vyas, Michelle Zheng, Emma Elliott, Changrui Xiao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlen A YuenDepartment of Neurology, Division of Neuro-oncology, University of California Irvine, Irvine, CA 92697, USA.ORCID 0000-0003-1950-8819
Eleanor ChuChao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA 92697, USA.ORCID 0000-0003-3788-1860
Ryan O'ConnellDepartment of Pathology, University of California Irvine, Irvine, CA 92697, USA.
Bryan K SunDepartment of Dermatology, University of California Irvine, Irvine, CA 92697, USA.
Raj VyasDepartment of Plastic & Aesthetic Surgery, University of California Irvine, Irvine, CA 92697, USA.
Michelle ZhengUC Irvine Charlie Dunlop School of Biological Sciences, University of California Irvine, Irvine, CA 92697, USA.
Emma ElliottDepartment of Psychology, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0009-0005-9153-727X
Changrui XiaoDepartment of Neurology, University of California Irvine, Irvine, CA 92697, USA.

Funding

UCI P30 Skin Center Systems Biology CoreP30AR075047 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI ANDERSEN, BOGI, GANESAN, ANAND K · 2019 to 2025
$5.1M
NIAMS NIH HHS P30 AR075047
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adultneurofibromatosis 1NF1plexiform neurofibromaselumetinibtargeted therapy

Identifiers

PMID40732327
PMCPMC12298819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.