ArticlePharmaceuticals (Basel, Switzerland)2025
Discovery of Cyclopentane-Based Phospholipids as Miltefosine Analogs with Superior Potency and Enhanced Selectivity Against
Ahmed H E Hassan, Hương Giang Lê, Tuấn Cường Võ, Minji Kim, Joo Hwan No, Mohamed H Aboutaleb, Jaehoon Sim, Byoung-Kuk Na, Yong Sup Lee
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In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
9 authors.
Ahmed H E HassanDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.ORCID 0000-0002-1048-6281 Hương Giang LêDepartment of Parasitology and Tropical Medicine, Department of Convergence Medical Science, Gyeongsang National University College of Medicine, Jinju 52727, Republic of Korea.
Tuấn Cường VõDepartment of Parasitology and Tropical Medicine, Department of Convergence Medical Science, Gyeongsang National University College of Medicine, Jinju 52727, Republic of Korea.
Minji KimDepartment of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Joo Hwan NoChemical and Structural Biology of Pathogens, Institut Pasteur Korea, Seongnam-si 13488, Republic of Korea.
Mohamed H AboutalebPharmaceutical Chemistry Department, Faculty of Pharmacy, Horus University, New Damietta 34518, Egypt.ORCID 0000-0002-3954-5783 Jaehoon SimDepartment of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul 02447, Republic of Korea.
Byoung-Kuk NaDepartment of Parasitology and Tropical Medicine, Department of Convergence Medical Science, Gyeongsang National University College of Medicine, Jinju 52727, Republic of Korea.ORCID 0000-0002-6734-1673 Yong Sup LeeDepartment of Pharmacy, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul 02447, Republic of Korea.ORCID 0000-0001-6523-6979 Funding
National Research Foundation of Korea (NRF) RS-2024-00333842
6 · The paper itselfAbstract
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Indexed as
miltefosine analogsNaegleria fowleripotential drugprimary amoebic meningoencephalitis
Identifiers
PMID40732274
PMCPMC12298883
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