Evidence map›Paper›PMID 40732264›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Is Anlotinib and Radiotherapy Combination Effective for Non-Small-Cell Lung Cancer with Brain Metastases? A Systematic Scoping Review and Meta-Analysis.

Helal F Hetta, Mostafa A Sayed Ali, Saleh F Alqifari, Hoda A Salem, Khulood A Qasem, Fawaz E Alanazi, Amirah Alhowiti, Amirah M Alatawi, Hyder Mirghani, Tariq Alrasheed and 7 more

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Helal F HettaDivision of Microbiology, Immunology and Biotechnology, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0001-8541-7304
Mostafa A Sayed AliDepartment of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-5851-5088
Saleh F AlqifariDepartment of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.
Hoda A SalemDepartment of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0001-6089-6062
Khulood A QasemCollege of Medicine, Sulaiman Alrajhi University, Al Bukairiyah 52726, Saudi Arabia.ORCID 0009-0008-7588-6252
Fawaz E AlanaziDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-8353-2066
Amirah AlhowitiDepartment of Family and Community Medicine, Faculty of Medicine, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0009-0009-0838-4620
Amirah M AlatawiDepartment of Family and Community Medicine, Faculty of Medicine, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0003-4638-9990
Hyder MirghaniDepartment of Internal Medicine, Faculty of Medicine, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-5817-6194
Tariq AlrasheedDepartment of Internal Medicine, Faculty of Medicine, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0009-0009-8239-5061
Salwa Q BukhariDiagnostic Radiology Department, Faculty of Medicine, University of Tabuk, P.O. Box 741, Tabuk 71491, Saudi Arabia.
Khalid A AlmazyadDepartment of Adult Medical Oncology, King Abdulaziz Medical City, Riyadh 14611, Saudi Arabia.
Sultan A AlhumaidDepartment of Family Medicine, King Salman Armed Forces Hospital, Tabuk 47512, Saudi Arabia.
Noura H Abd EllahDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Badr University in Assiut, Naser City 2014101, Egypt.
Hashim M AljohaniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madina 41477, Saudi Arabia.ORCID 0000-0001-5333-6956
Yasmin N RamadanDepartment of Microbiology and Immunology, Faculty of Pharmacy, Assiut University, Assiut 71515, Egypt.ORCID 0009-0008-7374-9334
Reem SayadDepartment of Histology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.ORCID 0000-0002-4378-2714

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anlotinibbrain metastasiscombined non-small-cell lung cancercranial radiotherapyCRTnovel multi-targeting tyrosine kinase inhibitorNSCLCradiotherapySRSstereotactic radiotherapyWBRTwhole-brain radiotherapy

Identifiers

PMID40732264
PMCPMC12298774

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.