Evidence map›Paper›PMID 40732261›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Development of a Novel Drug Delivery System "Nanoemulfoam" for Topical Delivery of Terbinafine Hydrochloride as a Repurposed Therapy in Skin Cancer: Formulation, Optimization, In Vitro Characterization, Ex Vivo Transdermal Permeability, Cytotoxicity Studies, and In Silico Assessment.

Abeer A Musallam, Reem A Aldeeb, Riham M Mansour, Manar Abd El-Karim Kassem, Doaa Fayez Saeed, Mahmoud A Mahdy, Rana M Abdelnaby, Hanan M Elnahas, Tarek M Ibrahim

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Relevance of topical application of minoxidil laden nano-lipid for hair growth enhancement.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abeer A MusallamDepartment of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza 12582, Egypt.ORCID 0000-0002-2956-0736
Reem A AldeebDepartment of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza 12582, Egypt.ORCID 0000-0002-7717-3925
Riham M MansourDepartment of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza 12582, Egypt.
Manar Abd El-Karim KassemDepartment of Pharmaceutical Chemistry, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza 12582, Egypt.
Doaa Fayez SaeedDepartment of Biochemistry, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza 12582, Egypt.
Mahmoud A MahdyDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Rana M AbdelnabyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Heliopolis University, Cairo 11785, Egypt.ORCID 0000-0001-7634-2240
Hanan M ElnahasDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-9148-3276
Tarek M IbrahimDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-9415-4267

Funding

Science, Technology and Innovation Funding Authority (STIFA/STDF) 47993
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cell viabilityD-optimal designdrug repurposingex vivo permeationnanoemulfoamskin cancerterbinafine hydrochloride

Identifiers

PMID40732261
PMCPMC12300454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.