Evidence map›Paper›PMID 40732240›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Resveratrol Alleviates Inflammatory Response Through P2X7/NLRP3 Signaling Pathway: In Silico and In Vitro Evidence from Activated Microglia.

Bianca Fagan Bissacotti, Marcylene Vieira da Silveira, Charles Elias Assmann, Priscila Marquezan Copetti, André Flores Dos Santos, Solange Binotto Fagan, João Augusto Pereira da Rocha, Maria Rosa Chitolina Schetinger, Vera Maria Melchiors Morsch, Nathieli Bianchin Bottari and 2 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bianca Fagan BissacottiGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.ORCID 0000-0001-6672-2530
Marcylene Vieira da SilveiraGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.ORCID 0000-0001-7825-3903
Charles Elias AssmannGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.ORCID 0000-0002-3524-3446
Priscila Marquezan CopettiGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.ORCID 0000-0003-1140-6236
André Flores Dos SantosGraduate Program in Nanosciences, Franciscan University (UFN), Santa Maria 97010-032, RS, Brazil.
Solange Binotto FaganGraduate Program in Nanosciences, Franciscan University (UFN), Santa Maria 97010-032, RS, Brazil.ORCID 0000-0002-8719-4228
João Augusto Pereira da RochaLaboratory of Modeling and Computational Chemistry, Federal Institute of Education, Science and Technology of Pará (IFPA), Bragança Campus, Bragança 68600-000, PA, Brazil.ORCID 0000-0002-3178-2362
Maria Rosa Chitolina SchetingerGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.ORCID 0000-0002-5240-8935
Vera Maria Melchiors MorschGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.
Nathieli Bianchin BottariDepartment of Microbiology and Parasitology, Federal University of Pelotas (UFPel), Pelotas 96010-610, RS, Brazil.
Alencar Kolinski MachadoGraduate Program in Nanosciences, Franciscan University (UFN), Santa Maria 97010-032, RS, Brazil.ORCID 0000-0003-2003-8420
Aleksandro Schafer da SilvaGraduate Program in Biological Sciences: Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, RS, Brazil.ORCID 0000-0001-5459-3823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain inflammationBV-2 cellsimmunomodulationpolyphenolpurinergic receptors

Identifiers

PMID40732240
PMCPMC12298262

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.