ArticleMicroorganisms2025
Polymicrobial Prosthetic Joint Infections: Unraveling Risk Factors and Outcomes in a Single-Center Study.
Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- The Microbiology of Postoperative Spine Surgical Site Infections: An Institutional Experience of 170 cases.Journal of clinical orthopaedics and trauma · 2026Article
- Convergent methodologies in prosthetic joint infection research: integrating transdisciplinary approaches to understand and prevent biofilm-driven failure of orthopaedic prostheses.Journal of medical microbiology · 2026Review
- Editorial for the Special Issue "Challenges of Biofilm-Associated Bone and Joint Infections".Microorganisms · 2026Article
- The infectome framework: linking polymicrobial ecology and biofilm dynamics to precision diagnostic approaches.Infection · 2026Review
- Can commensals alter pathogen's antibiotic resistance during co-culture?Journal of medical microbiology · 2026Article
- What constitutes a true polymicrobial periprosthetic joint infection? From multiple detections to organism-level causality.Frontiers in microbiology · 2026Review
- Article
- The proportion of chronic periprosthetic joint infection patients withJournal of bone and joint infection · 2026Article
- Reinfection and re-revision rates of periprosthetic knee infection under four different surgical strategies: a single centre retrospective observational study.Frontiers in cellular and infection microbiology · 2026Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic joint infection (PJI) is a serious complication after joint arthroplasty, with polymicrobial PJIs representing a distinct subset associated with worse outcomes. This study aims to characterize the risk factors, microbiological profiles, and clinical outcomes of polymicrobial PJIs in a single tertiary care center. A retrospective analysis was conducted on 499 patients diagnosed with PJI between 2010 and 2023. Polymicrobial infection was defined by isolation of ≥2 distinct pathogens from intraoperative samples. Demographic, microbiological, and clinical data were analyzed. Treatment success was defined as infection eradication without recurrence or chronic suppressive therapy. Polymicrobial PJIs accounted for 18.2% of cases. Patients with polymicrobial infections had higher rates of obesity, insulin-dependent diabetes, and higher Charlson comorbidity scores. Coagulase-negative staphylococci and gram-negative bacilli were more frequently isolated in polymicrobial infections, while
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