Evidence map›Paper›PMID 40732166›Full record

ArticleMicroorganisms2025

Healthy Ageing and Gut Microbiota: A Study on Longevity in Adults.

Lihua Deng, Jun Xu, Qian Xue, Yanan Wei, Jingtong Wang

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lihua DengDepartment of Geriatrics, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0002-7594-0414
Jun XuDepartment of Gastroenterology, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0002-4300-4824
Qian XueDepartment of Geriatrics, Peking University People's Hospital, Beijing 100044, China.
Yanan WeiDepartment of Geriatrics, Peking University People's Hospital, Beijing 100044, China.
Jingtong WangDepartment of Geriatrics, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0003-0878-2054

Funding

International Institute of Population Health, Peking University Health Science Center JKCJ202303National Project of Multidisciplinary Management of Major Diseases 2020
6 · The paper itself

Abstract

Many studies have focused on ageing and gut microbiota, but the correlation between gut microbiota and physical function in older adults, especially those with longevity, remains obscure and deserves further exploration. In this study we investigated changes in the gut microbiota and the association between gut microbiota and physical function in adults with longevity. This is a prospective observational study. Fifty-one older adults aged ≥ 60 years (including 27 participants aged 90 years and above) were enrolled. Information on clinical data, physical function including intrinsic capacity by Integrated Care for Older People (ICOPE) tool, and dietary habits of participants was collected and analysed. Gut microbiota structure and functional pathways were analysed by Metagenomics. Intrinsic capacity (measured as ICOPE scores) of adults' longevity (aged 90-98, longe group) was significantly lower than older adults aged 60-89 years (CON group) (5.44 ± 2.15 vs. 6.71 ± 1.46,

Indexed as

Akkermansia muciniphilafrailtygut microbiotahealthy ageingintrinsic capacity

Identifiers

PMID40732166
PMCPMC12298205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.