Evidence map›Paper›PMID 40732087›Full record

ArticleMicroorganisms2025

Five-Year Analysis of Microbial Keratitis Incidence, Isolates, and In Vitro Antimicrobial Sensitivity in the South West of England: An Epidemiological Study.

Poonam Sharma, Chimwemwe Chipeta, Kieran O'Kane, Alexander Whiteman, Bryher Francis, Richard Thornton, Indy Sian, Charlotte Buscombe, Jennifer Court, Nathaniel Knox-Cartwright and 1 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Current status on antimicrobial resistance in keratitis.Indian journal of ophthalmology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Poonam SharmaWest of England Eye Unit, Royal Devon University Healthcare NHS Foundation Trust, Exeter EX2 5DW, Devon, UK.
Chimwemwe ChipetaVision and Eye Research Institute, Anglia Ruskin University, Cambridge CB1 2LZ, Cambridgeshire, UK.ORCID 0000-0001-5139-3578
Kieran O'KaneDerriford Hospital, University Hospitals Plymouth NHS Foundation Trust, Plymouth PL6 8DH, Devon, UK.
Alexander WhitemanRoyal Cornwall Hospital, Royal Cornwall Hospitals NHS Trust, Truro TR1 3LJ, Cornwall, UK.
Bryher FrancisTorbay Hospital, Torbay and South Devon NHS Foundation Trust, Torquay TQ2 7AA, Devon, UK.
Richard ThorntonNorth Devon District Hospital, Royal Devon University Healthcare NHS Foundation Trust, Barnstaple EX31 4JB, Devon, UK.ORCID 0009-0007-4122-6937
Indy SianMusgrove Park Hospital, Somerset NHS Foundation Trust, Taunton TA1 5DA, Somerset, UK.
Charlotte BuscombeWest of England Eye Unit, Royal Devon University Healthcare NHS Foundation Trust, Exeter EX2 5DW, Devon, UK.
Jennifer CourtTorbay Hospital, Torbay and South Devon NHS Foundation Trust, Torquay TQ2 7AA, Devon, UK.
Nathaniel Knox-CartwrightWest of England Eye Unit, Royal Devon University Healthcare NHS Foundation Trust, Exeter EX2 5DW, Devon, UK.
Harry RobertsWest of England Eye Unit, Royal Devon University Healthcare NHS Foundation Trust, Exeter EX2 5DW, Devon, UK.ORCID 0000-0002-3590-0856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the incidence, causative organisms, and treatment effectiveness for microbial keratitis (MK) in the Southwest of England. Retrospective analysis of 872 corneal scrapes (January 2018-December 2022). Microbiology results were evaluated for organism growth and antimicrobial sensitivity. Data were divided into two groups for trend analysis (A: 2018-2020, B: 2021-2022). Of the 872 scrapes, 357 (39.6%) were culture positive. Bacteria accounted for 90.2% of cases, followed by viruses (2.8%), fungi (2.5%), mixed bacterial growth (2.5%), and Acanthamoeba (2.0%). The estimated incidence of MK was 9.69/100,000/year. Group B had a significantly higher overall MK incidence, with no change in pathogen distribution.

Indexed as

antibioticcultureempiricalmicrobial keratitissensitivity

Identifiers

PMID40732087
PMCPMC12297931

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.