Evidence map›Paper›PMID 40731988›Full record

ArticleMicroorganisms2025

Optimization of Fermentation Conditions for the Production of 2,3,5-Trimethylpyrazine by Recombinant

Xun Liu, Hongyi Gu, Handong Wang, Zhen Tang, Shuanglian Chen, Han Li, Wenli Quan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xun LiuSchool of Food and Liquor Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.ORCID 0000-0003-4502-3161
Hongyi GuSchool of Food and Liquor Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
Handong WangQinghai Provincial Key Laboratory of Crop Molecular Breeding, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China.
Zhen TangSchool of Food and Liquor Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
Shuanglian ChenSchool of Food and Liquor Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
Han LiSchool of Food and Liquor Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
Wenli QuanSchool of Food and Liquor Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.ORCID 0009-0006-9891-7408

Funding

Qinghai Provincial Key Laboratory of Crop Molecular Breeding 2023-1-1the Natural Science Foundation of Sichuan Province of China 2022NSFSC1782the Sichuan Province Scientific Research Foundation for the Returned Overseas Chinese Scholars 2022
6 · The paper itself

Abstract

2,3,5-Trimethylpyrazine (TMP) is an alkyl pyrazine with broad application prospects in the fields of food additives and medicine. L-threonine-3-dehydrogenase (TDH) is a key enzyme in the biosynthesis pathway of TMP. To explore the efficient and environmentally friendly production method of TMP, we constructed recombinant strains overexpressing the

Indexed as

2,3,5-trimethylpyrazineBacillus licheniformisBlTDH genefermentation optimizationrecombinant strains

Identifiers

PMID40731988
PMCPMC12298311

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.