Evidence map›Paper›PMID 40731839›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Nutritional Management of Liver Failure in the Intensive Care Unit.

Zsófia Verzár, Rudolf Kiss, Csaba Pál Bálint, Annamária Pakai, Tímea Csákvári

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zsófia VerzárInstitute of Emergency Care, Pedagogy of Health and Nursing Sciences, Faculty of Health Sciences, University of Pécs, H-7621 Pécs, Hungary.ORCID 0000-0001-5323-0748
Rudolf KissHeart Institute, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Csaba Pál BálintDoctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, H-7621 Pécs, Hungary.
Annamária PakaiInstitute of Emergency Care, Pedagogy of Health and Nursing Sciences, Faculty of Health Sciences, University of Pécs, H-7621 Pécs, Hungary.ORCID 0000-0002-2849-1310
Tímea CsákváriDepartment of Health Economics and Health Care Management, Institute of Health Insurance, Faculty of Health Sciences, University of Pécs, H-8900 Zalaegerszeg, Hungary.ORCID 0000-0002-3339-4953

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver failure, both acute and chronic, represents a complex, life-threatening condition frequently requiring intensive care unit (ICU) admission. Nutritional management is a crucial component of supportive therapy, aiming to mitigate catabolism, preserve lean body mass, and support immune and organ function. In acute liver failure (ALF), early nutritional intervention within 24-48 h and individualized energy-protein prescriptions are essential, even in the presence of hepatic encephalopathy. Chronic liver failure (CLF) and acute-on-chronic liver failure (ACLF) are often associated with severe malnutrition, sarcopenia, and systemic inflammation, necessitating tailored nutritional strategies. Subjective Global Assessment (SGA) and Royal Free Hospital Global Assessment (RFH-GA) tools are instrumental in identifying nutritional risk. Enteral nutrition (EN) is preferred across all stages, with parenteral nutrition (PN) reserved for contraindications. Special considerations include micronutrient repletion, prevention of refeeding syndrome, and perioperative nutritional support in transplant candidates and recipients. This clinical overview summarizes current evidence and guidelines on ICU nutrition in liver failure, emphasizing a multidisciplinary approach to improve outcomes.

Indexed as

Liver FailureNutritional SupportEnteral NutritionHumansIntensive Care UnitsMalnutritionParenteral Nutritionacute liver failurechronic liver failureintensive carenutritional management

Identifiers

PMID40731839
PMCPMC12299006

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.