Evidence map›Paper›PMID 40731580›Full record

ReviewMaterials (Basel, Switzerland)2025

Highly Filled Flowable Composite Resins as Sole Restorative Materials: A Systematic Review.

Konstantinos Tzimas, Eftychia Pappa, Maria Fostiropoulou, Efstratios Papazoglou, Christos Rahiotis

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Konstantinos TzimasDepartment of Operative Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-3718-4750
Eftychia PappaDepartment of Operative Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-1631-9871
Maria FostiropoulouDepartment of Operative Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0009-0008-0198-196X
Efstratios PapazoglouDepartment of Operative Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-5704-8297
Christos RahiotisDepartment of Operative Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-4117-3501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous need for simplified, minimally invasive restorative procedures with a high precision has led to the advancement of highly filled flowable resin-based materials. These materials present excellent initial outcomes in various clinical applications, including the injection molding technique. Given that several clinical reports present signs of wear and staining, this systematic review aims to investigate the mechanical and optical properties of highly filled flowable composite resins. A comprehensive literature research was conducted to identify relevant studies from the PubMed, the Cochrane Library, and Scopus databases. Data extraction and screening was performed by two independent evaluators. Both in vitro studies and clinical trials were included. A total of thirty-one studies were included in this review. A total of 27 in vitro studies investigated highly filled flowable composite resins independently, or in comparison with conventional composite resins, traditional flowable composites, bulk-fill flowable composites, glass ionomer cements, and compomers. Additionally, four randomized controlled clinical trials (RCTs) compared highly filled flowable composite resins with their conventional counterparts. Highly filled flowable composite resins exhibit adequate optical properties. Despite their significant improvements, their mechanical properties remain inferior to those of medium-viscosity composite resins. These materials demonstrate a favorable initial performance in the injection molding technique. Based on a limited number of RCTs, these materials demonstrate an adequate performance in class I and II restorations; however these findings should be interpreted with caution. The reported drawbacks in laboratory studies may contraindicate their clinical application in extensive cavities, load-bearing areas, and in cases of excessive tooth wear and parafunctional activity. A careful clinical case selection is strongly recommended.

Indexed as

biomaterialsdental materialflowable compositeoperative dentistrysystematic review

Identifiers

PMID40731580
PMCPMC12299359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.