Evidence map›Paper›PMID 40731288›Full record

ArticleBMC health services research2025

An episode-based cost analysis of virtual-first versus in-person-first care to treat common acute conditions among members of a large national payor.

Amanda L Zaleski, Xinbei Guan, Kelly J Thomas Craig, Christopher Junk, Arthur T McGill, Henry Gordon, Dorothea J Verbrugge, Kristofer Caya

Abstract read
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amanda L ZaleskiClinical Evidence Development, Aetna® Medical Affairs, CVS Health®, Wellesley, MA, USA.
Xinbei GuanAnalytics & Behavior Change, CVS Health, Wellesley, MA, USA.
Kelly J Thomas CraigClinical Evidence Development, Aetna® Medical Affairs, CVS Health®, Wellesley, MA, USA. craigk@aetna.com.
Christopher JunkAnalytics & Behavior Change, CVS Health, Wellesley, MA, USA.
Arthur T McGillAetna Network Virtual Care, CVS Health, Wellesley, MA, USA.
Henry GordonAetna Network Virtual Care, CVS Health, Wellesley, MA, USA.
Dorothea J VerbruggeClinical Evidence Development, Aetna® Medical Affairs, CVS Health®, Wellesley, MA, USA.
Kristofer CayaAetna Network Virtual Care, CVS Health, Wellesley, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential of virtual care as an alternative to in-person visits is promising, yet its economic impact is insufficiently understood. This evaluation represents an episode-based, cost impact analysis of virtual-first (versus in-person first) care to treat the most prevalent primary care acute conditions among Medicare Advantage (MA) and commercial fully-insured (C-FI) members of a large national health plan in the United States.

methodsRetrospective episodes-of-care and medical claims analyses identified members (N = 366,195; MA: 126,363, C-FI: 239,832) with resolved, pre-specified, acute primary care episodes (N = 455,231; MA: 141,034, C-FI: 314,197) between 1/1/2022-6/30/2022. Propensity score weighting estimated % difference in healthcare expenditures between virtual-first episodes and an adjusted cohort of in-person-first episodes.

resultsWithin the MA cohort, 7.6% (range: 0.7-24.8%) of episodes utilized virtual-first care with observed cost-of-episode 10-24% lower than in-person-first care for 6 of 11 included conditions (all P < 0.05), including: otolaryngology disease (-24 ± 2%), rhinitis (-20 ± 4%), gastroenterology disease (-20 ± 7%), minor bacterial skin infections (-17 ± 7%), sinusitis (-14 ± 4%), and bronchitis (-11 ± 4%). Within the C-FI cohort, 12.6% (range: 2.8-40.4%) of episodes utilized virtual-first care with observed cost-of-episode 9-33% lower than in-person-first care (all P < 0.001) for 12 of 16 included conditions (all P < 0.001), including: urinary tract infection (-33 ± 5%), viral skin infection (-29 ± 6%), gastroenterology disease (-27 ± 5%), rhinitis (-28 ± 5%), otolaryngology disease (-25 ± 2%), sinusitis (-25 ± 2%), urological disease (-23 ± 9%), contact dermatitis (-19 ± 5%), viral pneumonia (-17 ± 12%), bronchitis (-15 ± 4%), fungal skin infection (-11 ± 6%), and minor bacterial skin infection (-9 ± 7%), and 4 ± 2% higher to treat exposure to infectious disease (P = 0.001). There were no between-group differences in cost-of-episode to treat: skin inflammation (MA & C-FI), urinary tract infection (MA), exposure to infectious disease (MA), fungal skin infection (MA), low back pain (C-FI), or migraine headache (C-FI) (all P > 0.081).

conclusionThis real-world study of a large national sample of geographically diverse members demonstrates the potential of virtual-first care to resolve acute conditions at lower cost compared to in-person-first care. The use of episode-based analytical tools enhances the significance of these findings by enabling a proxy for clinical outcomes.

Indexed as

Episode of CarePrimary Health CareTelemedicineAcute DiseaseAdultAgedCosts and Cost AnalysisFemaleHealth ExpendituresHumansMaleMedicare Part CMiddle AgedRetrospective StudiesUnited StatesCare delivery, virtual carePrimary careTelehealthTelemedicine

Identifiers

PMID40731288
PMCPMC12309140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.