ArticleScientific reports2025
Biogenic synthesis of silver nanoparticles (AgNPs) from Allium jacquemontii extract and its assessment in different biological activities.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Nanotechnology is a vibrant and fast-developing field in science with diverse applications. Silver nanoparticles (AgNPs) are becoming gradually valuable because of their exceptional antimicrobial properties and remarkable physical characteristics. This study reports the phytochemical screening of Allium jacquemontii plant extract for the preparation of AgNPs. The prepared nanoparticles (NPs) were characterized via UV- spectroscopy, X-ray diffraction analysis (XRD), scanning electron microscopy (SEM), Fourier-transform infrared (FTIR) spectroscopy, and transmission electron microscopy (TEM) and were evaluated for antimicrobial and pharmacological activities. HPLC analysis showed that A. jacquemontii had the lowest quantity of ferulic acid (10.3 ppm) and the highest concentration of chlorogenic acid (317.9 ppm). The prepared AgNPs exhibited excellent antifungal potential against Aspergillus niger, with maximum growth inhibition of 64.4% while strong antibacterial activity of 14.3 mm against Escherichia coli at a dose of 10 mg/ml was found. Similarly, the highest antiparasitic activity was 75.41 ± 1.16 against Promastigote and 71.13 ± 0.12 against Amastigote at 200 µg/mg. Inhibition of glucosidase, and amylase was observed, suggesting potential antidiabetic properties. The AgNPs were found to be biofriendly with red blood cells (RBCs) of a healthy human. This study indicates the potential of A. jacquemontii inflorescence derived AgNPs.
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