ArticleBMC cancer2025
Clinical benefits of enhanced 3D-NEVERview sequence in MRI simulation for nasopharyngeal carcinoma patients received radiotherapy.
Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
background and purposeTo test whether the enhanced 3D-NEVERview (3D-NEVERview + C) sequence improves delineation accuracy and allows clinically meaningful dose reductions to the brachial plexus of nasopharyngeal carcinoma (NPC) with cervical lymph node metastasis in radiotherapy during MRI simulation. MATERIALS AND
methodsFifty NPC patients with cervical lymph node metastasis were enrolled. The contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), and contrast ratio (CR) of brachial plexus were compared between two different sequences. The volumes of brachial plexus delineated automatically (V
resultsCNR, SNR, and CR between two sequences showed statistical significance (P < 0.05). The volumes of V
conclusionThe 3D-NEVERview + C sequence significantly enhances the CR, thereby providing a clearer location of brachial plexus. In NPC patients with cervical lymph node metastasis, excessive doses to brachial plexus frequently occurred. Protecting brachial plexus during radiotherapy is crucial for reducing the risk of nerve injury. Therefore, incorporating the 3D-NEVERview + C sequence in MRI-sim is highly recommended.
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