ArticleBMC psychiatry2025
Association among objective and subjective sleep duration, depressive symptoms and all-cause mortality: the pathways study.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Insomnia, proteomic characteristics, and mortality risk in depression: a UK Biobank study.BMC psychiatry · 2026Article
- Comparison and validation of machine learning-based screening models for elevated depressive symptoms in peritoneal dialysis patients.Frontiers in public health · 2026Article
- Neurokinin Antagonists to Treat Vasomotor Symptoms-Possible Implications for Long-Term Health and Disease.Journal of clinical medicine · 2025Article
- Gut jet lag: how circadian rhythm disruption undermines the Chrono-Microbiota-Motility axis and induces functional constipation.Frontiers in nutrition · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundSleep deprivation and overload have been associated with increased risks of both depression and mortality. However, no study has quantitatively compared the effects of objective and subjective sleep duration on mortality or examined the mediating role of depressive symptoms in these associations.
methodsUtilizing data from the NHANES 2011-2014, this study employed structural equation modeling (SEM) to explore the impact of depressive symptoms, measured by Patient Health Questionnaire (PHQ-9) scores, on the relationship between both objective and subjective sleep durations and all-cause mortality.
resultsThe study included 7838 participants, comprising 4392 women (55.96%) with a mean age of 46.51 (0.46) years. Over a median 6.83-year follow-up, 582 deaths occurred. The restricted cubic spline curves demonstrated a J-shaped relationship between objective sleep duration and the all-cause mortality risk, and a U-shaped relationship between subjective sleep duration and the all-cause mortality risk. SEM analysis revealed that when subjective sleep duration was < 7 h/day, the indirect effect of sleep duration on all-cause mortality was - 0.013 (P = 0.003), and the mediation proportion of PHQ-9 scores was 40.63%. When objective sleep duration ≥ 7 h/day, the indirect effect of sleep duration on all-cause mortality was 0.003 (P = 0.028), and the mediation proportion of PHQ-9 scores was 2.10%.
conclusionsThe study confirmed a J-shaped and a U-shaped correlation for objective and subjective sleep duration with mortality risk. Depressive symptoms significantly mediated the association between shorter subjective sleep duration and mortality. This suggests that there is a need to focus on the co-morbidity of subjective sleep deprivation and depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.