ArticleNature immunology2025
PD-1 is requisite for skin T
Abstract read
In one paragraph
Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Host cell traversal by Plasmodium parasites drives sterilizing T cell-mediated immunity following immunization.Nature microbiology · 2026Article
- The CREM-IL-15 axis: decoding the persistence-exhaustion paradox in NK cell immunotherapy.Cancer immunology, immunotherapy : CII · 2026Review
- Epithelial-Dermal Immune Memory: TrackingInternational journal of molecular sciences · 2026Review
- PD-1⁺ CD8⁺ T cells: roles of PD-1 beyond an exhaustion marker.Seminars in immunopathology · 2026Review
- Microbiota and immune-related adverse events in cancer immunotherapy.Nature reviews. Cancer · 2026Review
- Human tissue-resident CD8 T cells contribute to trophoblast homeostasis in health and during acute inflammation.bioRxiv : the preprint server for biology · 2026Article
- T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Article
- Living rent free in your head: resident memory T cells.ImmunoHorizons · 2026Review
- Hidden immune memory niches in inflammatory skin diseases.bioRxiv : the preprint server for biology · 2026Article
- IL-4-STAT6 signaling delays protective CD8Nature immunology · 2026Article
- Role of MEG3-miRNAs in immune-inflammatory regulation in age-dependent wool follicle remodeling in Tan sheep.BMC genomics · 2026Article
- Balancing Intrinsic and Extrinsic Factors in CD8Immune network · 2026Review
- Understanding the Inflammatory Aspect of Osteoarthritis: Lessons from Immune Checkpoint Inhibitors.Journal of clinical medicine · 2026Review
- The Janus face of tissue-resident memory T cells: dual programming in tumor immune surveillance and autoimmune pathology.Frontiers in immunology · 2026Review
- Review
- Six degrees of TGFβ.Nature immunology · 2025Article
- Keeping it local: how CD8 TRMs regulate viral and cancer immunity.Frontiers in immunology · 2025Review
- Case Report: Tail-of-the-curve advantage from immune checkpoint inhibitor-anti-VEGF combination therapy: extended survival in a patient with metastatic lung adenocarcinoma.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
K Sanjana P Devi *Department of Dermatology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Eric Wang *Department of Dermatology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0009-0005-9564-2990
Abhinav JaiswalDepartment of Dermatology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Piotr KoniecznyDepartment of Immunology and Immunotherapy, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-4114-349X
Tae-Gyun KimDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, South Korea.
Christopher J NirschlDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7333-2757
Akanksha VermaInstitute for Computational Biomedicine, Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.
Yong LiuDepartment of Dermatology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-0196-3285
Julia MilczanowskiDepartment of Dermatology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Susan N ChristoDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Luke C GandolfoDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-3599-2455
Karyn HaitzDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, South Korea.
Trupti D VardamDepartment of Immunology, Mayo Clinic, Scottsdale, AZ, USA.ORCID http://orcid.org/0000-0003-1458-1902
Pinru WuDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Sandra L KingDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-9367-5354
Sze-Wah TseDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Komal PradhanDepartment of Dermatology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Xiaodong JiangDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Tian TianDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Robert C FuhlbriggeDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-0911-9310
Chrysalyne D SchmultsDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Rachael A ClarkDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
Thomas S KupperDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.ORCID http://orcid.org/0000-0002-4229-2916
Gordon J FreemanDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7210-5616
Laura K MackayDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-8496-6632
Shruti NaikDepartment of Immunology and Immunotherapy, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-2216-5135
Evan W NewellFred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
Olivier ElementoInstitute for Computational Biomedicine, Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-8061-9617
Mayte Suarez-FarinasDepartment of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-8712-3553
Niroshana AnandasabapathyDepartment of Dermatology, Englander Institute for Precision Medicine at Weill Cornell Medicine, New York, NY, USA. niroananda@gmail.com.ORCID http://orcid.org/0000-0002-0473-8358
Funding
Transgenic/KnockoutP01AI056299 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI SHARPE, ARLENE H. · 2003 to 2023
$42.5MDERMATOLOGY TRAINING GRANTT32AR007098 · NIAMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI THOMAS S. KUPPER · 1986 to 2026
$8.1MVaccination to generate protective tissue resident T cellsR01AI097128 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI CLARK, RACHAEL ANN, KUPPER, THOMAS S. · 2011 to 2015
$6.1MSKIN HOMING T CELLS--MOLECULAR CHARACTERIZATION OF CLAR01AI041707 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI KUPPER, THOMAS S. · 1997 to 2012
$4.1MInterrogating unique DC adaptations to tissue to promote barrier immunity and toleranceR01AR080436 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Niroshana Anandasabapathy · 2022 to 2026
$3.5MTransforming the diagnosis and care of patients with CTCL using TCR sequencingR01CA203721 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI CLARK, RACHAEL ANN, KUPPER, THOMAS S. · 2016 to 2020
$3.4MMechanisms of immune-epithelial crosstalk in tissue repairR01AI168462 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Shruti Naik · 2022 to 2026
$3.1MDecoding microbe-epithelial stem cell interactions in health and diseaseDP2AR079173 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NAIK, SHRUTI · 2020 to 2020
$2.5MNew mechanisms governing skin tissue residency memory T cellsR01AR083208 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Niroshana Anandasabapathy · 2024 to 2026
$2.1MCTCL immunobiology: lessons from alemtuzumabR01AR063962 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI CLARK, RACHAEL ANN · 2013 to 2017
$1.8MHarnessing the effects of Ror gamma t cells on epidermal stem cells and commensal microbes to promote efficient wound repairK22AI135099 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NAIK, SHRUTI · 2018 to 2019
$268kDecoding the repair and immunomodulatory functions of lymphatic vessels in wound healingR00AR083536 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PIOTR KONIECZNY · 2026 to 2026
$249kNCI NIH HHS R01 CA203721NIAID NIH HHS K22 AI135099NIAID NIH HHS P01 AI056299NIAID NIH HHS R01 AI041707NIAID NIH HHS R01 AI097128NIAID NIH HHS R01 AI168462NIAMS NIH HHS DP2 AR079173NIAMS NIH HHS K99 AR083536NIAMS NIH HHS R00 AR083536NIAMS NIH HHS R01 AR063962NIAMS NIH HHS R01 AR080436NIAMS NIH HHS R01 AR083208NIAMS NIH HHS T32 AR007098
Abstract
Tissue-resident memory T (T
Indexed as
CD8-Positive T-LymphocytesImmunologic MemoryMemory T CellsProgrammed Cell Death 1 ReceptorSkinTransforming Growth Factor betaAnimalsCell DifferentiationFemaleHumansMiceMice, Inbred C57BLMice, KnockoutSignal TransductionPDCD1 protein, humanPdcd1 protein, mouseProgrammed Cell Death 1 ReceptorTransforming Growth Factor beta
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.