ArticleNature immunology2025
Lymph-node-derived stem-like but not tumor-tissue-resident CD8
Abstract read
In one paragraph
Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Tumor-Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy-Immunotherapy Combination Trials.International journal of cancer · 2026Review
- Article
- Immune-pressure redistribution in resistance to PD-1/PD-L1 blockade: mechanisms, biomarkers, and therapeutic design.Molecular cancer · 2026Review
- Can Chemoradiotherapy Expand Immune Checkpoint Blockade Responsiveness in Mismatch Repair-Proficient Rectal Cancer?Annals of gastroenterological surgery · 2026Review
- Epigenetic plus cytokine therapy induces stem-like CD8Journal for immunotherapy of cancer · 2026Article
- Motherhood's immune legacy reshapes the breast for lasting cancer defence.Immuno-oncology technology · 2026Article
- Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer.Nature immunology · 2026Article
- DC-intrinsic SHP1 restrains central memory CD8⁺ T cell formation via the TCF-1/Wnt/β-Catenin axis.Medical oncology (Northwood, London, England) · 2026Article
- New insights into progenitor exhausted T cell populations.Nature reviews. Immunology · 2026Article
- Single-cell gain-of-function mapping reveals latent regulatory programs governing CD8Research square · 2026Article
- T Cell Exhaustion as a Regulated Differentiation Programme.European journal of immunology · 2026Review
- Lymphatic egress recycles tumor-experienced effector CD8 T cells to sustain immune surveillance.bioRxiv : the preprint server for biology · 2026Article
- Uncoupling tumor immunogenicity from cell death with platinum(IV)-antibody conjugates.National science review · 2026Article
- T-cell Priming by High-Avidity Neoantigens in Lymph Nodes Augments Adoptive Immunotherapy.Cancer immunology research · 2026Article
- The CD8 immgenT framework as a universal reference of mouse CD8αβ T cell differentiation states.bioRxiv : the preprint server for biology · 2026Article
- Redirecting cytomegalovirus immunity against pancreas cancer for immunotherapy.Journal for immunotherapy of cancer · 2026Article
- Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer.Cell reports. Medicine · 2026Article
- Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential.bioRxiv : the preprint server for biology · 2026Article
- Dual Bcl-2/Bcl-xl inhibition via AZD0466 combines with immune checkpoint blockade to enhance anti-tumour activity.Cell death & disease · 2026Article
- Immune remodeling of tumor-draining lymph nodes: mechanistic determinants of checkpoint blockade responsiveness.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Sharanya K M Wijesinghe *Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0002-0798-6226
Lisa Rausch *Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.
Sarah S GabrielDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0002-6359-485X
Giovanni GallettiIRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0001-6613-2354
Marco De LucaIRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0001-8310-5526
Lei QinDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.
Lifen WenDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0003-0229-7306
Carlson TsuiDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0003-0642-814X
Kevin ManDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0002-6585-9532
Leonie HeydenDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0009-0001-2018-8747
Teisha MasonDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.
Lewis D NewlandDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0009-0004-0327-8910
Andrew KuehThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Yang LiaoOlivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.ORCID http://orcid.org/0000-0002-9746-2839
David ChisangaOlivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.ORCID http://orcid.org/0000-0002-0421-3957
Julian SwatlerIRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0001-8710-2808
Emanuele VoulazIRCCS Humanitas Research Hospital, Rozzano, Italy.
Giuseppe MarulliIRCCS Humanitas Research Hospital, Rozzano, Italy.
Valentina ErricoIRCCS Humanitas Research Hospital, Rozzano, Italy.
Agnese LosurdoIRCCS Humanitas Research Hospital, Rozzano, Italy.
Gustavo R RossiFrazer Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Queensland, Australia.
Fernando Souza-Fonseca-GuimaraesFrazer Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Queensland, Australia.ORCID http://orcid.org/0000-0002-2037-8946
Nicholas D HuntingtonBiomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0002-5267-7211
Thomas GebhardtDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0002-3768-9468
Daniel T UtzschneiderDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.ORCID http://orcid.org/0000-0003-2205-9057
Marco J HeroldThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Wei ShiOlivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia.
Jan SchroederDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia.
Enrico LugliIRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0002-1964-7678
Axel KalliesDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Queensland, Australia. axel.kallies@unimelb.edu.au.ORCID http://orcid.org/0000-0002-6312-6968
Funding
Department of Health | National Health and Medical Research Council (NHMRC) 1147409Department of Health | National Health and Medical Research Council (NHMRC) 1194482Department of Health | National Health and Medical Research Council (NHMRC) 2003934Department of Health | National Health and Medical Research Council (NHMRC) 2017420
Abstract
CD8
Indexed as
CD8-Positive T-LymphocytesLymph NodesLymphocytes, Tumor-InfiltratingNeoplasmsAnimalsHumansImmune Checkpoint InhibitorsMiceMice, Inbred C57BLTransforming Growth Factor betaImmune Checkpoint InhibitorsTransforming Growth Factor beta
Identifiers
PMID
40730900What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.