Evidence map›Paper›PMID 40730882›Full record

ArticleScientific reports2025

LC-MS/MS quantification of omadacycline in human plasma for therapeutic drug monitoring: method development and clinical application.

Yueyuan Wang, Zhipeng Diao, Yuchen Qu, Kai Fan, Chen Feng, Bo Lv, Yunli Yu, Zhou Geng

Abstract readEvaluation StudyValidation Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yueyuan WangDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.ORCID http://orcid.org/0009-0009-4955-0859
Zhipeng DiaoDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.
Yuchen QuDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.
Kai FanDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.
Chen FengDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.
Bo LvDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.
Yunli YuDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China. haoyyl0902@163.com.
Zhou GengDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China. gengzhouaa@163.com.

Funding

Jiangsu Pharmaceutical Association A202428Wellcome Trust 214185
6 · The paper itself

Abstract

Omadacycline, a third-generation tetracycline antibiotic, exhibits time-dependent pharmacokinetics. The ratio of the 24-hour area under the concentration-time curve to minimum inhibitory concentration (AUC

Indexed as

Anti-Bacterial AgentsDrug MonitoringLiquid Chromatography-Mass SpectrometryTandem Mass SpectrometryTetracyclinesAgedAged, 80 and overCalibrationEndocannabinoidsFemaleHumansLinear ModelsMaleMicrobial Sensitivity TestsMiddle AgedReproducibility of ResultsAnti-Bacterial AgentsEndocannabinoidsomadacyclineTetracyclinesLC-MSOmadacyclinePlasmaTherapeutic drug monitoring

Identifiers

PMID40730882
PMCPMC12307862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.