Evidence map›Paper›PMID 40730713›Full record

ArticleMolecular neurobiology2025

Effects and Mechanisms of NMDAR-EphB2 on Synapses in Mice by Active Immunization with a GluN1 Peptide.

Kai Qian, Youshi Meng, Lin Zhang, Lanfeng Sun, Sijie Ou, Rida Li, Chi Gong, Shengyu Yang, Yuan Wu

Abstract read
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kai Qian *Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Youshi Meng *Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Lin Zhang *Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Lanfeng SunDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Sijie OuDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Rida LiDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Chi GongDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Shengyu YangDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China. shengyuyangysy@163.com.
Yuan WuDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China. nwuyuan90@163.com.

Funding

the National Natural Science Foundation of China 82360267
6 · The paper itself

Abstract

This study investigated the expression of N-methyl-D-aspartate receptor(NMDAR)-EphB2 and associated changes in hippocampal neuronal dendritic spines and synaptic ultrastructure in an anti-NMDAR encephalitis mouse model. Utilizing the GluN1

Indexed as

ImmunizationNerve Tissue ProteinsPeptidesReceptor, EphB2Receptors, N-Methyl-D-AspartateSynapsesAnimalsDendritic SpinesHippocampusMaleMiceMice, Inbred C57BLNeuronsSeizuresEphb2 protein, mouseGprin1 protein, mouseNerve Tissue ProteinsPeptidesReceptor, EphB2Receptors, N-Methyl-D-AspartateAnti-NMDAR encephalitisEphB2GluN1 peptide-immunized miceSeizureSynaptic plasticity

Identifiers

PMID40730713
PMCPMC12559109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.