ArticleScientific reports2025
Preoperative albumin-to-fibrinogen ratio as a predictor of postoperative hospital stay in locally advanced esophageal squamous cell carcinoma after neoadjuvant therapy.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophageal squamous cell carcinoma (ESCC) is a major global health issue, with postoperative hospital length of stay (LOS) being a critical factor influencing patient outcomes and healthcare costs. This study evaluates the impact of preoperative albumin-to-fibrinogen ratio (AFR) and albumin-to-D-II aggregates ratio (ADR) on LOS in patients with locally advanced ESCC undergoing neoadjuvant therapy. A retrospective study of 135 patients with locally advanced ESCC who underwent esophagectomy after neoadjuvant therapy (July 2013-November 2020). Demographic, clinical, and preoperative blood data were analyzed. LOS was defined from surgery to discharge. AFR and ADR values were calculated, and ROC curves identified optimal cutoffs. Multivariate Cox proportional hazards models and Kaplan-Meier analysis were used to assess relationships between AFR and LOS. The optimal AFR cutoff was 10.34, demonstrating better predictive accuracy for LOS than ADR. High AFR was associated with significantly shorter LOS. Multivariate analysis revealed high AFR, and cholesterol were linked to shorter stays, while older age and high globulin levels were associated with longer stays. Kaplan-Meier analysis confirmed the relationship. Preoperative AFR is a reliable predictor of LOS in advanced ESCC patients after neoadjuvant therapy, offering potential for improved clinical management and resource allocation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.