Evidence map›Paper›PMID 40730620›Full record

ArticleScientific reports2025

The association between muscle strength and z scores of pulmonary function.

Laura Petraglia, Klara Komici, Leonardo Bencivenga, Giuseppe Rengo, Raffaella Pagliaro, Angela Sciattarella, Nicola Ferrara, Andrea Bianco, Germano Guerra

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura Petraglia *Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Klara Komici *Department of Medicine and Health Sciences, University of Molise, Via Giovanni Paolo II, 86100, Campobasso, Italy. klara.komici@unimol.it.
Leonardo BencivengaDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Giuseppe RengoDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Raffaella PagliaroDepartment of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.
Angela SciattarellaDepartment of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.
Nicola FerraraDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Andrea BiancoDepartment of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.
Germano GuerraDepartment of Medicine and Health Sciences, University of Molise, Via Giovanni Paolo II, 86100, Campobasso, Italy.

Funding

Investment PE8-Project Age-It: "Ageing Well in an Ageing Society". This resource was cofinanced by Next Generation EU DM 1557 11.10.2022Molise CTE D33B22000060001
6 · The paper itself

Abstract

Z scores and percent predicted values of spirometry parameters are widely used for the evaluation of pulmonary function and detection of respiratory diseases. Decreased pulmonary function should correlate with reduction of muscle strength although it is unclear whether z scores of respiratory parameters are associated with muscle strength. In a cohort of 398 adults, pulmonary function assessment and muscle strength measurement by handgrip strength and physical activity level were evaluated. Probable sarcopenia was defined by muscle strength reduction. Univariate and multivariate regression analysis and ROC curve were applied. The AUC for FEV1 and FVC were significantly greater than the z FEV1 and z FVC (p = 0.0004 and p = 0.0008) respectively. Multivariate regression analysis adjusted for confounders also reported a significant and independent relationship between z FEV1; z FVC and HGS measurements. FEV

Indexed as

LungMuscle StrengthSarcopeniaAdultAgedFemaleForced Expiratory VolumeHand StrengthHumansMaleMiddle AgedRespiratory Function TestsROC CurveSpirometryVital CapacityAgeingFEV1FVCMuscle strengthZ FEV1Z FVC

Identifiers

PMID40730620
PMCPMC12307799

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.