Evidence map›Paper›PMID 40730418›Full record

Trial reportBMJ mental health2025

Implementing work-related Mental-health guidelines in general PRacticE (IMPRovE): findings of a parallel cluster randomised controlled trial.

Danielle Mazza, Vera Camões-Costa, Karen Nolidin, Samantha Chakraborty, Justin Kenardy, Bianca Brijnath, Duncan Mortimer, Joanne Enticott, Michael Kidd, Lyndal J Trevena and 2 more

Abstract readRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Danielle MazzaDepartment of General Practice, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia danielle.mazza@monash.edu.ORCID 0000-0001-6158-7376
Vera Camões-CostaDepartment of General Practice, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-0305-0575
Karen NolidinDepartment of General Practice, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Samantha ChakrabortyDepartment of General Practice, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Justin KenardyThe University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-9475-8450
Bianca BrijnathSchool of Humanities and Social Sciences, La Trobe University, Melbourne, Victoria, Australia.ORCID 0000-0002-0536-6859
Duncan MortimerCentre for Health Economics, Monash University Faculty of Business and Economics, Clayton, Victoria, Australia.
Joanne EnticottMonash Centre for Health Research and Implementation, Monash University, Clayton, Victoria, Australia.
Michael KiddCentre for Future Health Systems, University of New South Wales, Sydney, New South Wales, Australia.
Lyndal J TrevenaSydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-1419-1832
Sharon ReidSpeciality of Addiction Medicine, Central Clinical School, Faculty of Medicine and Health, Tha\e University of Sydney, Sydney, New South Wales, Australia.
Alex CollieHealthy Working Lives Research Group, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Funding

the National Health and Medical Research Council (NHMRC) ID - APP1160223
6 · The paper itself

Abstract

backgroundMental health conditions arising from work are a rapidly increasing burden for individuals, employers and society, and are challenging to diagnose and treat.

objectiveTo assess the effectiveness of a multicomponent intervention on increasing general practitioners' (GPs') adherence to the 'Clinical guideline for the diagnosis and management of work-related mental-health conditions in general practice' (the Guideline) and improve patient work and health and work outcomes.

methodsPragmatic hybrid III parallel cluster randomised controlled trial involving Australian GPs and their patients. GP clinics were randomly assigned to receive the intervention (GP participation in an academic detailing session, enrolment into a virtual community of practice, and receipt of resources). Those assigned to the control group received no support related to the implementation of the Guideline. GP adherence to guideline recommendations was assessed at baseline and 9 months postbaseline, using virtual simulated patient scenarios (vignettes) describing a diverse range of patient circumstances. Patient work and health outcomes (using the 21-item Depression and Anxiety Stress Scale and 36-item short-form) were assessed using self-report surveys.

findingsThirty-eight intervention clusters (52 GPs) and 36 control clusters (46 GPs) contributed to the primary outcome data. Intervention clusters had significantly higher adherence scores than control clusters, by 0.98 points on a 0-9 scale (95% CI 0.38 to 1.58) with a Cohen's d of 0.67. Patients recruited from 30 intervention (n=99) and 17 control (n=55) clusters contributed to the secondary outcome data. No differences were detected for patients' work or health outcomes due to an underpowered sample.

conclusionsGP adherence to the Guideline improved as a result of receiving the multicomponent intervention. IMPLICATIONS: Purposively designed multicomponent implementation strategies to increase guideline-concordant care should be incorporated into guideline production activities and operationalised with guideline release to facilitate evidence-based care. TRIAL REGISTRATION NUMBER: ACTRN12620001163998, November 2020.

Indexed as

General PracticeGeneral PractitionersGuideline AdherenceMental DisordersPractice Guidelines as TopicAdultAustraliaFemaleHumansMaleMiddle AgedDepression & mood disorders

Identifiers

PMID40730418
PMCPMC12306257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.