Evidence map›Paper›PMID 40729459›Full record

ArticleJournal of veterinary pharmacology and therapeutics2026

Comparing Pharmacokinetics of Meloxicam When Administered With a Needle-Free Injection Device Versus Needle-And-Syringe in Piglets.

Minh Man Pham, Terri L O'Sullivan, Maria Del Rocio Amezcua, Saad Enouri, Yu Gu, Zvonimir Poljak, Jennifer M Reinhart, Ron Johnson

Abstract readComparative Study
In one paragraph

Article in Journal of veterinary pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minh Man PhamDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0009-0007-8595-6114
Terri L O'SullivanDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0000-0001-5687-0185
Maria Del Rocio AmezcuaDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Saad EnouriDepartment of Biomedical Science, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0009-0001-1372-816X
Yu GuDepartment of Biomedical Science, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0000-0002-3434-2039
Zvonimir PoljakDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Jennifer M ReinhartDepartment of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.ORCID https://orcid.org/0000-0002-3021-5075
Ron JohnsonDepartment of Biomedical Science, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0000-0002-3857-9295

Funding

Canadian Global Food Animal Residue Avoidance Databank (CgFARAD)Ontario Ministry of Agriculture, Food and Agribusiness (OMAFA) 102162Ontario Pork 22/2008OVC Fellowship Program
6 · The paper itself

Abstract

Meloxicam is a common analgesic for castration in pigs. While needle-free technology is effective for swine vaccination, its implementation for administering meloxicam has not been fully explored. The objective of this study was to compare the pharmacokinetics (PK) of meloxicam administered via a commercial needle-free injection device (NFID) and intramuscularly via needle-and-syringe (NS) in nursing piglets. Twenty-six nursing piglets were randomly assigned to one of two treatment groups receiving the same approved label dosage of 0.4 mg/kg of meloxicam. Plasma meloxicam concentrations were measured using liquid chromatography-tandem mass spectrometry, and PK profiles were measured using non-compartmental analysis. The results indicated C

Indexed as

Anti-Inflammatory Agents, Non-SteroidalMeloxicamAnimalsArea Under CurveHalf-LifeInjections, IntramuscularMaleSwineAnti-Inflammatory Agents, Non-SteroidalMeloxicamanimal welfaredrug deliverymeloxicamneedle‐free injectionpiglet processingswine

Identifiers

PMID40729459
PMCPMC12796778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.