Evidence map›Paper›PMID 40729285›Full record

ArticleReports (MDPI)2024

Optimization of Collagen Scaffold with Cultured Autologous Chondrocytes for Osteochondritis Dissecans of the Knee: A Case Report.

Nicolas Valladares, Gibran J Jacobo-Jimenez, Nathaniel Lara-Palazuelos, Maria G Zavala-Cerna

Abstract readCase Reports
In one paragraph

Article in Reports (MDPI), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicolas ValladaresSports Medicine Division, Rehabilitem, Guadalajara 44100, Mexico.
Gibran J Jacobo-JimenezSports Medicine Division, Rehabilitem, Guadalajara 44100, Mexico.
Nathaniel Lara-PalazuelosUnidad Académica Ciencias de la Salud, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico.
Maria G Zavala-CernaUnidad Académica Ciencias de la Salud, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico.ORCID 0000-0001-6508-9657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of osteochondritis dissecans of the knee has always been a challenge for orthopedic surgeons. We present a case report of a 38-year-old male with severe right knee pain after suffering from an indirect trauma and axial rotation of the knee, limiting knee functionality and impeding his ability to walk, with a diagnosis of osteochondritis dissecans in the trochlea of the knee, who underwent arthroscopic treatment with matrix-induced autologous chondrocyte implantation (MACI). After the surgery, a physical therapy protocol for MACI was implemented, and magnetic resonance images with cartilage mapping were used to evaluate the recovery of the lesion. A total recovery was observed and evaluated with the modified Cincinnati knee rating system (mCKRS). A discussion is provided with evidence and general recommendations for the use of MACI in the treatment of adult OCD of the knee as a possible alternative to conventional treatments. Our case shows a rapid improvement in pain and functionality 2 months after surgery that progressed to full recovery within 6 months.

Indexed as

cartilage defectcase reportclinical outcomesmatrix-induced autologous chondrocyte implantationosteochondritis dissecans

Identifiers

PMID40729285
PMCPMC12225332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.