Evidence map›Paper›PMID 40729254›Full record

ArticleReports (MDPI)2024

Serious and Progressive Neuropathy Presumably Post-Shingrix Vaccination.

Michael J Wons, Avani Vaghela, Amna Khalid, Benjamin D Brooks

Abstract readCase Reports
In one paragraph

Article in Reports (MDPI), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael J WonsDepartment of Biomedical Sciences, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0009-0002-9232-9745
Avani VaghelaDepartment of Biomedical Sciences, Rocky Vista University, Ivins, UT 84738, USA.
Amna KhalidDepartment of Biomedical Sciences, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0009-0005-2985-1495
Benjamin D BrooksDepartment of Biomedical Sciences, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0000-0001-7456-3074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of serious and progressive neuropathy shortly following the administration of the herpes zoster subunit (HZ/su) vaccine, otherwise known as Shingrix. The progressive neuropathy occurred a week following the vaccination and progressed until discharge 16 days post-admittance. The patient's mild symptoms persist. The development of neuropathy following HZ/su administration is exceedingly rare, with an attributable risk of three cases per million vaccines administered. A black box warning was issued for this indication, although diagnosis and treatment were not confirmed for this patient. Reporting cases like this is crucial for a comprehensive understanding of vaccine risks and to characterize the underlying etiology of these serious adverse events.

Indexed as

neuropathyShingrixvaccinevaricella

Identifiers

PMID40729254
PMCPMC12225469

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.