ArticleThe Gerontologist2025
Does caregiver stress get under the skin? Associations with care recipient inflammation.
Article in The Gerontologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
BACKGROUND AND
objectivesA wealth of research has focused on the caregiving stress process, while less is devoted to understanding how caregiver stress may impact health outcomes in the care recipient. We examine whether higher levels of caregiver role overload will be associated with care recipients' C-reactive protein (CRP) concentrations, an inflammatory biohormone. Additionally, this study observed whether caregivers' positive and negative appraisals of caregiving moderated this association. RESEARCH DESIGN AND
methodsData are drawn from the 2017 National Health and Aging Trends Study (NHATS) and associated National Study of Caregiving (NSOC). CRP levels were assessed via dried blood spot sample. We examine the main effect of caregiver role overload on care recipient CRP, adjusting for care recipient demographics and care context. Separate models were run on the interaction of overload with emotional difficulty of care and caregiving gains to test whether appraisal of care moderates the association between caregiving overload and care recipient CRP.
resultsCare recipients were predominantly female (63.72%) and averaged 78.32 years old. Caregiving role overload was positively associated with care recipient CRP concentrations (B = 0.06, β = 0.08, SE = 0.25, p = .02). No significant interaction was observed between caregiving gains or caregiving emotional difficulty in predicting CRP. DISCUSSION AND IMPLICATIONS: Care recipients demonstrated greater CRP concentrations when their caregiver reported higher role overload, regardless of their appraisal of the care context. Efforts to help caregivers delegate tasks or offer respite may reduce overload and have positive impact on care recipients' physiological health.
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