ArticleReports (MDPI)2023
A Multiple Synergic Treatment for Non-Healing Ulcer Management in a Patient with
Cristina Vocca, Gianmarco Marcianò, Vincenzo Rania, Luca Catarisano, Caterina Palleria, Salvatore Ciranni, Giuseppina Torcia, Raffaele Serra, Francesco Monea, Giuseppe Spaziano and 3 more
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In one paragraphArticle in Reports (MDPI), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Cristina VoccaOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Gianmarco MarcianòOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Vincenzo RaniaOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0002-9938-5259 Luca CatarisanoOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Caterina PalleriaOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Salvatore CiranniVascular Surgery Unit, Department of Medical and Surgical Science, University Magna Graecia, 88100 Catanzaro, Italy.
Giuseppina TorciaVascular Surgery Unit, Department of Medical and Surgical Science, University Magna Graecia, 88100 Catanzaro, Italy.
Raffaele SerraVascular Surgery Unit, Department of Medical and Surgical Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0003-4477-7412 Francesco MoneaResearch Center FAS@UMG, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Giuseppe SpazianoDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0002-1906-5109 Giovambattista De SarroOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0002-7629-6579 Rita CitraroOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0001-6746-6751 Luca GallelliOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco University Hospital", Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0003-0858-7902 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Klippel-Trenanauy syndrome (KTS) is a rare genetic disease determined by overexpression of the phosphatidylinositol-4-5-bisphosphate 3 kinase catalytic subunit (PIK3CA) gene. The clinical presentation is characterized by venous and capillary malformations and lymphatic malformation. To date, no definitive treatment has been suggested in order to improve the clinical symptoms related to the developments of a skin wound. In this case, we describe a young man with KTS that developed a severe skin wound in the lower right limb unresponsive to the common treatment but responsive to a treatment with oxygen-ozone therapy, pulsed magnetic fields (diamagnetic treatment), and topical fixed association of cocum caprylate, oleic acid, quercetin, and 18-β glycyrrhetinic acid. This is the first case that supports a multistep approach to treat a rare and severe disease, and we hope that other studies can support our data.
Indexed as
Klippel–Trenanauy syndromenutrientsoxygen-ozone therapypulsed magnetic fieldswound
Identifiers
PMID40729201
PMCPMC12225347
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