Evidence map›Paper›PMID 40729181›Full record

ArticleReports (MDPI)2023

Abnormalities in Regional Cerebral Blood Flow Due to Headache in a COVID-19 Infected Patient Observed on 99mTC-ECD Brain SPECT/CT.

Ya-Chun Chu, Shin-Tsu Chang, Hung-Yen Chan, Daniel Hueng-Yuan Shen, Hung-Pin Chan

Abstract read
In one paragraph

Article in Reports (MDPI), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ya-Chun ChuDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City 81314, Taiwan.
Shin-Tsu ChangDepartment of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Kaohsiung City 813414, Taiwan.ORCID 0000-0003-4005-2094
Hung-Yen ChanDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City 81314, Taiwan.
Daniel Hueng-Yuan ShenDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City 81314, Taiwan.
Hung-Pin ChanDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City 81314, Taiwan.ORCID 0000-0001-9741-5824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 31-year-old man was diagnosed with a COVID-19 infection, presenting with a diffuse headache and an uneven sensation of fullness, despite having no prior systemic diseases. 99mTc-ECD Brain SPECT/CT revealed a marked decrease in blood perfusion in the cerebral cortices, predominantly in the frontal region and involving the olfactory sulcus. In contrast, there was increased perfusion in the occipital lobe and asymmetrical perfusion in the cerebellum. This case highlights changes in regional blood flow perfusion that might affect the functional connectivity of the pain matrix, leading to the onset of headaches and associated underlying mechanisms.

Indexed as

99mTc-ECD brain SPECT/CTCOVID-19 infectionheadachepain-matrixregional cerebral blood flow

Identifiers

PMID40729181
PMCPMC12225477

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.