Evidence map›Paper›PMID 40729151›Full record

ArticleReports (MDPI)2024

Descending Necrotizing Mediastinitis in Healthy Young Adults: The Fatal Consequence of the Delayed Help.

Petar Uchikov, Maria Kraeva, Krasimir Kraev, Bozhidar Hristov, Dzhevdet Chakarov, Nedzhat Ali, Chavdar Stefanov, Angelina Mollova-Kyosebekirova, Tihomir Tenchev, Snezhanka Dragusheva and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Reports (MDPI), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Petar UchikovDepartment of Special Surgery, Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.
Maria KraevaDepartment of Otorhynolaryngology, Medical Faculty, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.
Krasimir KraevDepartment of Propedeutics of Internal Diseases, Medical Faculty, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-1155-117X
Bozhidar HristovSection "Gastroenterology", Second Department of Internal Diseases, Medical Faculty, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-2943-1766
Dzhevdet ChakarovDepartment of Propedeutics of Surgical Diseases, Section of General Surgery, Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.
Nedzhat AliDepartment of Special Surgery, Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-7264-9277
Chavdar StefanovDepartment of Anaesthesiology, Emergency and Intensive Care Medicine, Medical Faculty, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Angelina Mollova-KyosebekirovaDepartment of General and Clinical Pathology, Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0001-5461-409X
Tihomir TenchevDepartment of Special Surgery, Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-5682-6886
Snezhanka DragushevaDepartment of Nursing Care, Faculty of Public Health, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.
Elizabet DzhambazovaFaculty of Public Health, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0009-0000-7678-5703
Bistra Dobreva-YatsevaSection "Cardiology", First Department of Internal Diseases, Medical Faculty, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-0295-7434

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDescending necrotizing mediastinitis is one of the most lethal forms of acute mediastinitis. It originates from an odontogenic or deep neck infection, which descends to the mediastinum through the fascial planes. It is a rare condition, but mortality rates remain high, especially in the presence of comorbidities or predisposing factors. Delay in diagnosis has been shown to be one of the most important factors for the disease outcome. Therefore, early diagnosis and treatment by a multidisciplinary team are of utmost importance. CASE SERIES: Four healthy young males with descending necrotizing mediastinitis were treated at our institution. None of them had any comorbidities, but all of them waited between 3 and 4 days before seeking medical help. Upon their arrival at the hospital, in addition to the presence of a severe neck infection, the presence of mediastinitis was also found. Despite the timely surgical treatment of both the source of the infection and the mediastinitis, three of the four cases had a fatal outcome.

conclusionWe believe that the time factor is of greater importance for the outcome of acute descending mediastinitis than the factors of age and presence of accompanying diseases. Proper and rapid treatment by a multidisciplinary team is essential, even for young and healthy people.

Indexed as

deep neck infectionsmediastinitismultiorgan failuresepsistoothacheyoung adults

Identifiers

PMID40729151
PMCPMC12225399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.