Evidence map›Paper›PMID 40729144›Full record

ArticleReports (MDPI)2024

Proton Pump Inhibitors Induced Hyponatremia in a Liver Transplanted Patient-The Role of Deprescribing: A Case Report and Literature Review.

Gianmarco Marcianò, Benedetto Caroleo, Luca Catarisano, Donatella Cocchis, Caterina Palleria, Giovambattista De Sarro, Luca Gallelli

Abstract readCase Reports
In one paragraph

Article in Reports (MDPI), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Association betweenFrontiers in pharmacology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gianmarco MarcianòOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco" University Hospital, 88100 Catanzaro, Italy.ORCID 0000-0003-1478-9551
Benedetto CaroleoOperative Unit of Internal Medicine, Soverato Hospital, ASP7 Catanzaro, 88100 Catanzaro, Italy.
Luca CatarisanoOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco" University Hospital, 88100 Catanzaro, Italy.ORCID 0000-0003-0532-9924
Donatella CocchisDepartment of Liver Transplants, Citta Della Salute Hospital, 10126 Torino, Italy.
Caterina PalleriaOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco" University Hospital, 88100 Catanzaro, Italy.
Giovambattista De SarroOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco" University Hospital, 88100 Catanzaro, Italy.ORCID 0000-0002-7629-6579
Luca GallelliOperative Unit of Pharmacology and Pharmacovigilance, "Renato Dulbecco" University Hospital, 88100 Catanzaro, Italy.ORCID 0000-0003-0858-7902

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplant patients are frail subjects due to lifelong therapy with immunosuppressants. In these patients, comorbidity and polytherapy increase the risk of adverse drug reactions. In this study, we report the development of hyponatremia, probably related to pantoprazole in a liver transplant patient. Sertraline dismission and treatment with sodium chloride did not improve clinical symptoms and laboratory levels. Pantoprazole dismission induced an improvement in clinical symptoms and the normalization of sodium levels. A five-month follow-up revealed the absence of clinical symptoms and normal serum sodium levels.

Indexed as

adverse drug reactiondeprescribinghyponatremiaimmunosuppressantsliver transplantpantoprazole

Identifiers

PMID40729144
PMCPMC12225499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.