ArticleAsian Pacific journal of cancer prevention : APJCP2025
Investigations of Cu2ONPs - Orange Peels: Biosynthesis, Characterization, and Anticancer Activity on a Cytotoxic Breast Cancer Cell Line.
Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Characterization and preliminary cytotoxic effects of pomegranate peel extract-loaded nanoparticles on HepG2 cells.Scientific reports · 2026Article
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3 authors.
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Abstract
backgroundThe study aimed to evaluate the efficacy of nanocomposites extracted from orange peels in targeting and combating MCF-7 cells.
methodsWe characterized the nanoparticles using XRD, FTIR, SEM, and GC-MS, and evaluated their cytotoxicity and activity using the MTT colorimetric assay and double staining technique.
resultsThe obtained results showed that the nanoparticles ranged from 19 to 66 nanometers in size and contained active compounds in the range of 4,000-500 cm⁻¹. However, the XRD sizes of the crystalline nanoparticles ranged from 15 to 23 nm. Orange peel contains important compounds such as octanal, 1, 6-octadien-3-ol, 3, 7-dimethyl, and limonene. At 800 mg/ml, DPPH can act as a strong antioxidant and reduce free radicals by 78.29%. The addition of the molecules resulted in a trace amount of 3.99%, a viability of 74.671%, and a half-maximal inhibitory concentration of 43.75 g/mL for the cell line. The compatibility with the low concentration effectively repaired the damaged cells.
conclusionsWe expect the present study to provide important insights into the influence of molecular structure on anti-cancer action.
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