Evidence map›Paper›PMID 40728974›Full record

ReviewCurrent issues in molecular biology2025

Systematic Review on the Importance of Gut Microbiota in the Regulation of Type 2 Diabetes Through Physical Activity and Exercise.

Luis Muguerza-Rodríguez, Alba Mier, Jesus G Ponce-González, Cristina Casals, Juan Corral-Pérez

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luis Muguerza-RodríguezExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0009-0001-8692-5041
Alba MierExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.
Jesus G Ponce-GonzálezExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-5982-7761
Cristina CasalsExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-6992-0492
Juan Corral-PérezExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-6574-9827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes (T2D) is a major global health issue, influenced by sedentary behavior and obesity. Emerging evidence implicates the gut microbiota in T2D pathophysiology through effects on glucose metabolism, inflammation, and insulin sensitivity. This systematic review included eleven studies, six observational and five interventional, examining the relationship between physical activity, exercise, and gut microbiota in individuals with or at risk of T2D. Observational studies associated low physical activity and high sedentary time with reduced α-diversity and increased abundance of potentially harmful bacteria. Interventional studies showed that structured exercise, including moderate-intensity and sprint interval training, increased beneficial bacteria such as

Indexed as

insulin resistanceintestinal dysbiosismetabolic diseasesobesity

Identifiers

PMID40728974
PMCPMC12293346

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.