ArticleGeroScience2026
Health-related quality of life trajectories and loss of independence among community-dwelling older adults.
Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors influencing long-term health-related quality of life among intensive care unit survivors: a mixed-methods systematic review.Frontiers in public health · 2026Pooled it
- Predictive analysis of health-related quality of life trajectories in older patients with chronic pain based on explainable machine learning models.Health and quality of life outcomes · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Health-related quality of life (HRQOL) is a key determinant of loss of independence (LOI) among older adults. However, the relationship between late-life HRQOL trajectory patterns and the risk of LOI remains unclear. This study utilized 5-year longitudinal data from the Sukagawa Study, and group-based trajectory modeling. HRQOL trajectories were analyzed using the mental component scale (MCS) and physical component scale (PCS) from the SF-8. Hazard ratios (HRs) and 95% confidence intervals (CIs) for LOI or death were calculated using Cox proportional hazards regression. Among 4043 participants (median age 78.8 years, interquartile range [IQR] 75.8-82.5; 56% women), HRQOL change score trajectories were categorized as decline, stable, and increase for MCS (11.7%, 81.0%, 7.2%) and PCS (10.9%, 81.4%, 7.6%). Over a mean follow-up of 66.4 months (IQR 48.0-73.0), LOI or death incidence was 42.5 per 1000 person-years (95% CI 39.8-45.2). Compared to the stable group, MCS decline was associated with higher LOI or death risk (HR 1.51, 95% CI 1.04-2.18), and an increase was associated with lower risk (HR 0.26, 95% CI 0.11-0.57). PCS decline was linked to higher LOI risk (HR 1.66, 95% CI 1.17-2.37), while an increase showed no significant association (HR 1.07, 95% CI 0.61-1.89). Longitudinal HRQOL trajectory is closely related to LOI risk among community-dwelling older adults. A declining trajectory in physical and mental components is strongly associated with higher LOI risk, while an increasing trajectory in the mental component is possibly associated with lower risk.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.