Evidence map›Paper›PMID 40728741›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

[

Matti Raitza, Markus Wolfien, Heiko Lemcke, Ralf Gäbel, Praveen Vasudevan, Moritz Schweins, Tobias Lindner, Markus Joksch, Anna Schildt, Jens Kurth and 8 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Translational perspective on myocardial αEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  3. The molecular symphony of myocardial repair: RGD, FAPI, and granzyme B PET in concert.European journal of nuclear medicine and molecular imaging · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Matti Raitza *Department of Cardiac Surgery, Rostock University Medical Center, 18057, Munich, Germany.
Markus Wolfien *Institute of Medical Informatics and Biometry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, 01307, Dresden, Germany.
Heiko LemckeDepartment of Cardiac Surgery, Rostock University Medical Center, 18057, Munich, Germany.
Ralf GäbelDepartment of Cardiac Surgery, Rostock University Medical Center, 18057, Munich, Germany.
Praveen VasudevanDepartment of Cardiac Surgery, Rostock University Medical Center, 18057, Munich, Germany.
Moritz SchweinsDepartment of Cardiac Surgery, Rostock University Medical Center, 18057, Munich, Germany.
Tobias LindnerCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 18057, Rostock, Germany.
Markus JokschCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 18057, Rostock, Germany.
Anna SchildtCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 18057, Rostock, Germany.
Jens KurthDepartment of Nuclear Medicine, Rostock University Medical Center, 18057, Rostock, Germany.
Änne GlassInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, 18057, Rostock, Germany.
Alper ÖnerDepartment of Cardiology, Rostock University Medical Center, 18057, Rostock, Germany.
Hüseyin InceDepartment of Cardiology, Rostock University Medical Center, 18057, Rostock, Germany.
Felix G MeinelInstitute of Diagnostic and Interventional Radiology, Rostock University Medical Center, 18057, Rostock, Germany.
Bernd Joachim KrauseDepartment of Nuclear Medicine, Rostock University Medical Center, 18057, Rostock, Germany.
Brigitte VollmarRudolf-Zenker-Institute for Experimental Surgery, Rostock University Medical Center, 18057, Rostock, Germany.
Robert DavidDepartment of Cardiac Surgery, Rostock University Medical Center, 18057, Munich, Germany.
Cajetan Immanuel LangDepartment for Preventive Sports Medicine and Sports Cardiology, Technical University of Munich, School of Medicine and Health, TUM University Hospital, Munich, Germany. cajetan.lang@mri.tum.de.ORCID 0000-0001-6775-8068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAngiogenesis is crucial in myocardial healing after myocardial infarction (MI). The α

methodsCardiac magnetic resonance imaging (CMR) was used to assess cardiac function and morphology after 28 days in two groups: permanent ligation (PL) of the left anterior descending coronary artery and transient occlusion for 30 min (I/R). Following these measurements, hearts were excised for histological and immunohistological examinations to evaluate scar formation, capillary density, and cellular composition. PET imaging with [

resultsBoth infarct models induced scar formation, with the PL group developing large infarcts accompanied by massive left ventricular dilation and hypertrophy of cardiomyocytes, while the I/R group exhibited small intramural scars without significant changes in LV geometry or function. PET imaging revealed significantly higher tracer accumulation in the infarct area of the PL group compared to the I/R group. Single-nucleus transcriptomics performed 5 days post-MI revealed that angiogenesis markers were enriched in the I/R group, while the highest α

conclusionActivated fibroblasts are the primary target cells of [

Indexed as

AcetatesFibroblastsHeterocyclic CompoundsHeterocyclic Compounds, 1-RingMyocardial InfarctionNeovascularization, PhysiologicOligopeptidesAngiogenesisAnimalsGallium RadioisotopesIntegrin alphaVbeta3MalePositron-Emission TomographyRats1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane1,4,7-triazacyclononane-N,N',N''-triacetic acidAcetatesarginyl-glycyl-aspartic acidGallium RadioisotopesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingIntegrin alphaVbeta3OligopeptidesAngiogenesisFibroblastsGa-NODAGA-RGD-PETMouse modelMyocardial infarction

Identifiers

PMID40728741
PMCPMC12830458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.