ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026
Incidence trends of colorectal cancer in young adults in Spain.
Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Artificial Intelligence-Enabled Analysis of WNT Pathway Dysregulation in Bevacizumab-Treated Early-Onset Colorectal Cancer.International journal of molecular sciences · 2026Article
- Hemorrhoids and Rectal Cancer: A Systematic Review of Clinical Overlap, Diagnostic Misclassification, and Early Detection Strategies for Primary Care.Journal of multidisciplinary healthcare · 2026Review
- What cancers are increasing in young adults: a population-based study of incidence trends in adults 20-49 years old in the South of Spain.BMC public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the 1990s, the incidence of early-onset colorectal cancer (EOCRC) and other cancers sharing risk factors with CRC, has been increasing in numerous countries, particularly in high-income settings. This increase shows a birth cohort effect, possibly due to a progressive Westernization of lifestyles resulting from exposure to risk factors during early life, with their delayed effects on incidence. Until 2016, in Spain, the increase in the incidence of EOCRC was limited to those aged 20-29 years, and this phenomenon may gradually affect older age groups, albeit later than in other Western countries. Although the absolute number of EOCRC cases is low, the increasing incidence in younger age groups indicates changes in risk factor exposure and likely heralds an increase in the future cancer burden. This increase highlights the need for research, diagnosis, treatment, public health awareness, and initiatives to mitigate the growing burden of EOCRC, but does not justify, at this time, reducing the age at which screening begins.
Indexed as
Identifiers
40728704What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.