Evidence map›Paper›PMID 40728581›Full record

ArticleDermatologie (Heidelberg, Germany)2025

[Noninvasive imaging of cutaneous melanoma metastases : Microenvironment and vascular insights in therapy].

Oliver Mayer, Rebecca Schönherr, Julia Welzel, Sandra Schuh

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Dermatologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oliver MayerKlinik für Dermatologie und Allergologie, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland. oliver.mayer@uk-augsburg.de.
Rebecca SchönherrKlinik für Dermatologie und Allergologie, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland.
Julia WelzelKlinik für Dermatologie und Allergologie, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland.
Sandra SchuhKlinik für Dermatologie und Allergologie, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsMelanomaSkin NeoplasmsTomography, Optical CoherenceTumor MicroenvironmentHumansIpilimumabMaleMiddle AgedNivolumabIpilimumabNivolumabImmunotherapyMalignant melanomaNeoplasm metastasisNoninvasive imagingOptical coherence tomography

Identifiers

PMID40728581
PMCPMC12672726

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.