ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025
Burden of macular complications in Japanese patients aged 75 years and over with sarcoid uveitis.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Blood-Ocular Barrier Dysfunction in Uveitis: A Bidirectional Model Linking Pathogenesis, Clinical Monitoring, and Therapeutic Opportunities.Medical sciences (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeTo investigate the epidemiology and complications of sarcoid uveitis in older Japanese patients.
methodsA single-center, retrospective cohort study. Medical records of patients aged ≥ 65 years with sarcoid uveitis at the Institute of Science Tokyo Hospital between 2012 and 2022 were analyzed.
resultsOf 37 patients (73 eyes) included, mean age was 72.9 ± 6.3 years; male-to-female ratio was 1:4.3. Anatomically, most patients had panuveitis (67.6%) or anterior uveitis (18.9%). Ocular symptoms were the most common initial presentation (89.2%). Ocular complications occurred in all eyes, most frequently cataract (80.8%), glaucoma (47.9%), and ocular hypertension (37.0%). Macular complications occurred in 35.6% of eyes and were significantly more frequent in patients aged ≥ 75 years than in those aged 65-74 years (60% vs. 14%; p < 0.0001). The proportion of eyes with best-corrected visual acuity ≤ 0.1 logMAR is 58.1% at baseline, 58.3% at 6 months, 52.3% at 1 year, and 68.8% at 3 years.
conclusionOur study uniquely identifies patients aged ≥ 75 years as a previously unrecognized high-risk group for macular complications (60% vs. 14% in those aged 65-74 years). In this cohort of older Japanese patients with sarcoid uveitis, we observed a female predominance, predominantly bilateral panuveitis, and frequent ocular complications including cataract, glaucoma, and ocular hypertension. Ocular symptoms were the typical initial presentation, and early recognition with prompt intervention is critical to prevent irreversible vision loss and optimize visual outcomes in this vulnerable population.
Indexed as
Identifiers
40728574What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.