Evidence map›Paper›PMID 40728570›Full record

ArticlePharmacogenomics

From bench to bedside: a spotlight on pharmacogenomics at Nemours Children's Health.

Kelsey J Cook, Nathan D Seligson, Benjamin Q Duong, Vicky L Funanage, Susan M Kirwin, Edward B Mougey, Stephen Lawless, David West, Pamela H Arn, Kathryn V Blake

Abstract read
In one paragraph

Article in Pharmacogenomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kelsey J CookBiomedical Research, Nemours Children's Health, Jacksonville, FL, USA.
Nathan D SeligsonBiomedical Research, Nemours Children's Health, Jacksonville, FL, USA.
Benjamin Q DuongBiomedical Research, Nemours Children's Health, Wilmington, DE, USA.
Vicky L FunanageBiomedical Research, Nemours Children's Health, Wilmington, DE, USA.
Susan M KirwinBiomedical Research, Nemours Children's Health, Wilmington, DE, USA.
Edward B MougeyBiomedical Research, Nemours Children's Health, Jacksonville, FL, USA.
Stephen LawlessBiomedical Research, Nemours Children's Health, Wilmington, DE, USA.
David WestBiomedical Research, Nemours Children's Health, Wilmington, DE, USA.
Pamela H ArnBiomedical Research, Nemours Children's Health, Jacksonville, FL, USA.
Kathryn V BlakeBiomedical Research, Nemours Children's Health, Jacksonville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nemours Children's Health (NCH) is a large, multi-state pediatric health system in the United States with hospitals and outpatient locations across Delaware, New Jersey, Pennsylvania, and Florida. NCH has maintained consistent effort in pharmacogenomic (PGx) research through the Center for Pharmacogenomics and Translational Research since 2003. In 2018, NCH funded the development of a dedicated Clinical Pharmacogenomics Service (CPGxS) to support PGx testing and return of results across the NCH enterprise. The CPGxS consultant-based service provides clinical PGx testing and supports PGx-focused research. Over the past seven years, the CPGxS has developed an in-house PGx testing platform, integrated a PGx clinical decision support (CDS) system into the electronic medical record (EHR), established a comprehensive consultant clinic, and provided a broad variety of education opportunities for providers, patients, and trainees. In this institutional profile, we highlight the development of a PGx program and related efforts across a multi-state pediatric-specific healthcare system.

Indexed as

Child HealthPharmacogeneticsTranslational Research, BiomedicalChildDecision Support Systems, ClinicalElectronic Health RecordsHumansUnited Statesclinical decision supportclinical implementationconsult serviceeducationimplementation sciencepediatricsPharmacogeneticsprecision medicine

Identifiers

PMID40728570
PMCPMC12427439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.