Evidence map›Paper›PMID 40728402›Full record

ArticleRadiology2025

Quantitative Ultrashort Echo Time MRI for Evaluation of Sciatic Nerve Degeneration and Regeneration in Rat Models.

Yuanshan Wu, Yajun Ma, Xin Cheng, Kaixin Pan, James Lo, Elisabeth Orozco, Junyuan Chen, Saeed Jerban, Michael P Andre, Jiang Du and 2 more

Abstract read
In one paragraph

Article in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Yuanshan WuResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.ORCID 0009-0008-5842-3969
Yajun MaDepartment of Radiology, University of California, San Diego, Calif.
Xin ChengResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.
Kaixin PanResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.ORCID 0009-0000-1429-6744
James LoResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.ORCID 0000-0002-7351-0752
Elisabeth OrozcoResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.
Junyuan ChenDepartment of Radiology, University of California, San Diego, Calif.ORCID 0000-0002-4973-7244
Saeed JerbanResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.
Michael P AndreResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.ORCID 0000-0001-8744-4808
Jiang DuResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.
Eric Y ChangResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.ORCID 0000-0003-3633-5630
Sameer B ShahResearch Service, VA San Diego Healthcare System,9500 Gilman Dr, MC 0863, San Diego, CA 92093-0683.ORCID 0000-0001-6613-3904

Funding

Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
CSRD VA I01 CX002118NIAMS NIH HHS R01 AR079484
6 · The paper itself

Abstract

Background Evaluating peripheral nerve response after injury or repair remains a critical clinical challenge. Current medical imaging approaches provide limited insight into the degenerative or regenerative environment of affected nerves. Purpose To assess the efficacy of ultrashort echo time (UTE) quantitative MRI (qMRI) for evaluating peripheral nerve degeneration and regeneration in rat models of sciatic nerve injury and to assess correlations between UTE qMRI parameters and histologic findings. Materials and Methods In this animal study conducted from November 2022 to December 2023, four experimental groups were created in 6-8-week-old male Lewis rats:

Indexed as

Magnetic Resonance ImagingNerve DegenerationNerve RegenerationPeripheral Nerve InjuriesSciatic NerveAnimalsDisease Models, AnimalMaleRatsRats, Inbred Lew

Identifiers

PMID40728402
PMCPMC12314773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.